Results 161 to 170 of about 527,565 (212)
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Modelling risks in disease mapping
Statistical Methods in Medical Research, 2006In this article, we propose a strategy of analysis of mortality data with the aim of providing a guideline for epidemiologists and public health researchers to choose a reasonable model for estimating mortality (or incidence) risks. Maps displaying the crude mortality rates or ratios are usually misleading because of the instability of the estimators ...
Ugarte, M. D. +2 more
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Issues in the mapping of two diseases
Statistical Methods in Medical Research, 2005Recently, there has been increased interest in the geographical modelling of two or more diseases. In this article, we consider a number of issues relating to such an endeavour including the standardization process and the comparison of univariate and bivariate disease mapping models.
Dabney, Alan R., Wakefield, Jon C.
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Mixture models and disease mapping
Statistics in Medicine, 1993AbstractThe analysis and recognition of disease clustering in space and its representation on a map is one of the oldest problems in epidemiology. Some traditional methods of constructing such a map are presented. An alternative approach using mixture models to identify population heterogeneity and map construction within an empirical Bayes framework ...
P, Schlattmann, D, Böhning
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Strategies in complex disease mapping
Current Opinion in Genetics & Development, 2000Dissecting the genetics of common, complex disorders remains one of the great challenges in human genetics. The acceleration of human genome sequence determination, improvements in informatics, large-scale identification of single nucleotide polymorphisms and improvements in scoring technologies have now increased the feasibility of identifying ...
G C, Johnson, J A, Todd
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Statistical Methods in Medical Research, 2005
This article discusses and extends statistical models to jointly analyse the spatial variation of rates of several diseases with common risk factors. We start with a review of methods for separate analyses of diseases, then move to ecological regression approaches, where the rates from one of the diseases enter as surrogate covariates for exposure ...
Held, Leonhard +4 more
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This article discusses and extends statistical models to jointly analyse the spatial variation of rates of several diseases with common risk factors. We start with a review of methods for separate analyses of diseases, then move to ecological regression approaches, where the rates from one of the diseases enter as surrogate covariates for exposure ...
Held, Leonhard +4 more
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Approximate inference for disease mapping
Computational Statistics & Data Analysis, 2006zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Laurie M. Ainsworth, Charmaine B. Dean
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Reliability-adjusted disease maps
Social Science & Medicine, 1995Bayesian methods for adjusting mortality and morbidity rates to account for variations caused by small numbers are presented. Although such methods produce statistically biased morbidity and mortality rate estimates, these approaches are superior for any applications that depend on a relative ordering of a set of rates because the total error of ...
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NIMBLE for Bayesian Disease Mapping
Spatial and Spatio-temporal Epidemiology, 2020This tutorial describes the basic implementation of Bayesian hierarchical models for spatial health data using the R package nimble. To quote the nimble R description: A system for writing hierarchical statistical models largely compatible with 'BUGS' and 'JAGS', writing nimbleFunctions to operate models and do basic R-style math, and compiling both ...
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Linkage Disequilibrium Maps and Disease-Association Mapping
2007Over the last few years, association mapping of disease genes has developed into one of the most dynamic research areas of human genetics. It focuses on identifying functional polymorphisms that predispose to complex diseases. Population-based approaches are concerned with exploiting linkage disequilibrium (LD) between single-nucleotide polymorphism ...
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Gene mapping of ocular diseases
Survey of Ophthalmology, 1992Increasing awareness of the role of genetic factors in the causation of many human eye diseases has made ocular genetics one of the fastest growing areas of ophthalmology. The objective of this paper is to present the basic principles of gene mapping and their application to ophthalmology.
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