Results 171 to 180 of about 10,577,757 (334)

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Accuracy of Dengue Reporting by National Surveillance System, Brazil

open access: yesEmerging Infectious Diseases, 2016
Monaise M.O. Silva   +12 more
doaj   +1 more source

Apple Watch for Hypertension Screening. [PDF]

open access: yesHypertension
Cohen JB   +5 more
europepmc   +1 more source

Annual Report Concerning Foodborne Disease in New Zealand, 2009 [PDF]

open access: yes, 2010
Cressey, Peter   +3 more
core  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Confiabilidade do diagnóstico final de dengue na epidemia 2001-2002 no Município do Rio de Janeiro, Brasil

open access: yesCadernos de Saúde Pública
Este estudo analisou a confiabilidade do diagnóstico final das 155.242 notificações de dengue da epidemia 2001-2002 no Município do Rio de Janeiro, fornecidas pela Secretaria Municipal de Saúde do Rio de Janeiro, por meio do Sistema de Informação de ...
Ana Lucia Araujo de Toledo   +3 more
doaj  

Reported Tuberculosis Symptoms: An Inadequate Classifier of Disease State. [PDF]

open access: yesClin Infect Dis
McCreesh N   +5 more
europepmc   +1 more source

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