Results 101 to 110 of about 6,660,576 (307)

A study on predictive nomogram for abdominal wall hernia in peritoneal dialysis patients based on multicenter data

Frontiers in Medicine
PurposeThis study aims to develop and externally validate a scoring nomogram based on three key indicators (Peritoneal dialysis vintage, age, and albumin) to predict the risk of developing abdominal wall hernia in patients with end-stage renal disease ...
Yugang Cao, Tao Fang, Jun Guo, Sha-sha Peng, Jin Yang   +4 more
doaj   +1 more source

Vascular Disease, Non‐Steroidal Anti‐Inflammatory Drugs and Risk of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives A history of vascular disease has been shown to be associated with an increased risk of Parkinson's disease, but this may be due to reverse causation. In addition, non‐steroidal anti‐inflammatory drugs are thought to reduce Parkinson's disease risk, but evidence is inconsistent and confounding by prior vascular disease is possible ...
Clare Wotton, Carol Hermon, Sarah Floud, Gillian Reeves, Isobel Barnes   +4 more
wiley   +1 more source

Analysis of prognostic prediction and nursing intervention value in PD patients based on nomogram model

Frontiers in Medicine
ObjectiveTo explore the independent risk factors for technical survival in patients undergoing peritoneal dialysis (PD), construct a nomogram model for predicting 1-, 3-, and 5-year technical survival rates, and validate the clinical value of nursing ...
Yugang Cao, Tao Fang, Jun Guo, Xun Hu, Jin Yang   +4 more
doaj   +1 more source

Neuronal Stress and Injury Caused by HIV-1, cART and Drug Abuse: Converging Contributions to HAND

Brain Sciences, 2017
Multiple mechanisms appear to contribute to neuronal stress and injury underlying HIV-associated neurocognitive disorders (HAND), which occur despite the successful introduction of combination antiretroviral therapy (cART).
Ana B. Sanchez, Marcus Kaul
doaj   +1 more source

Innate Immunity and its Implications on Pathogenesis of Inflammatory Bowel Disease

, 2010
This chapter contains sections titled: Introduction Overview of the innate immune system Expression of TLRs in health and disease General role of TLRs and Nods: maintenance of barrier function, induction of IgA and expression of antimicrobial peptides ...
Fukata, Masayuki, Breglio, Keith, Abreu, Maria T   +2 more
core   +1 more source

Pathogenesis of Alzheimer's Disease [PDF]

Journal of the Royal Society of Medicine, 1987
C G, Hamon, J A, Blair
openaire   +2 more sources

Inebilizumab in AQP4‐Seropositive NMOSD: One‐Year Follow‐Up From a Multicenter, Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Real‐world evidence on inebilizumab among neuromyelitis optica spectrum disorder (NMOSD) patients is lacking. This study assessed inebilizumab among Chinese patients with aquaporin 4 autoantibody (AQP4‐IgG)‐seropositive NMOSD in a real‐world setting.
Mengcui Gui, Jiayang Zhan, Wei Li, Tao Jin, Dan He, Daishi Tian, Zhijun Li, Jing Lin, Yue Li, Hongyu Zhou, Bitao Bu   +10 more
wiley   +1 more source

Machine learning-based prediction of recurrent extrahepatic bile duct stones after common bile duct exploration: a comparative study of models and SHAP-driven interpretability analysis

Frontiers in Medicine
PurposeThis study aimed to construct and compare machine learning models for predicting recurrent extrahepatic bile duct stones after common bile duct exploration and to clarify the contribution of key risk factors using SHAP analysis, thereby providing ...
Yugang Cao, Xun Hu, Jun Guo, Tao Fang
doaj   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Experimental Models to Study the Pathogenesis and Treatment of Mucormycosis

Mucormycosis presents a formidable challenge to clinicians and researchers. Animal models are an essential part of the effort to decipher the pathogenesis of mucormycosis and to develop novel pharmacotherapeutics against it.
Ronen Ben-Ami
core   +1 more source