Results 91 to 100 of about 6,660,576 (307)

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Pneumococcal Virulence Gene Expression and Host Cytokine Profiles during Pathogenesis of Invasive Disease

, 2008
Copyright © 2008, American Society for Microbiology Data source: , https://doi.org/10.1128/IAI.01161-07 Link to a related website: http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC2223468&blobtype=pdf, Open Access via UnpaywallPneumococcal disease ...
James C. Paton, Ogunniyi, Abiodun D., LeMessurier, Kim S., Le Messurier, K., Kim S. LeMessurier, Mahdi, Layla K., Paton, James C., Ogunniyi, A., Abiodun D. Ogunniyi, Layla K. Mahdi, Paton, J., Mahdi, L.   +11 more
core   +1 more source

Ménétrier’s Disease: Its Mimickers and Pathogenesis [PDF]

, 2016
Ménétrier’s disease is a rare protein-losing hypertrophic gastropathy. Histologically, it can be mistaken for other disorders showing hypertrophic gastropathy.
Mary Kay Washington, Robert J. Coffey, Won Jae Huh   +2 more
core   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

Use of a highly-sensitive rapid diagnostic test to screen for malaria in pregnancy in Indonesia

Malaria Journal, 2020
Background The sensitivity of rapid diagnostic tests (RDTs) for malaria is inadequate for detecting low-density, often asymptomatic infections, such as those that can occur when screening pregnant women for malaria.
Vera T. Unwin, Rukhsana Ahmed, Rintis Noviyanti, Agatha M. Puspitasari, Retno A. S. Utami, Leily Trianty, Theda Lukito, Din Syafruddin, Jeanne R. Poespoprodjo, Maria A. Santana-Morales, Feiko O. Ter Kuile, Emily R. Adams   +11 more
doaj   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

Activation of the zona incerta GABAergic circuit for the treatment of pain hypersensitivity in Parkinson’s disease mice model

The Journal of Headache and Pain
Background Pain is a prevalent and frequently undertreated non-motor symptom in Parkinson’s disease (PD), affecting approximately 40% to 85% of patients.
Juntao Cui, Junliang Qian, Yaying Shi, Yanhong Liu, Le Qu, Wenting Jia, Junxia Xie, Limin Shi   +7 more
doaj   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Pathogenesis of Borna disease [PDF]

, 1993
Borna disease represents a unique model of a virus-induced immunological disease of the brain. Naturally occurring in horses and sheep, the mechanisms of pathogenesis have been studied in experimental animals, namely in the rat. Many investigations have revealed that the infection of the natural hosts principally follows the same pathogenic pathways as
L, Stitz, T, Bilzer, J A, Richt, R, Rott
openaire   +2 more sources

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source