Results 71 to 80 of about 12,664,100 (362)

The Role of Pro-Inflammatory Cytokines in the Pathogenesis of Cardiovascular Disease

International Journal of Molecular Sciences
With cardiovascular disease (CVD) being a primary source of global morbidity and mortality, it is crucial that we understand the molecular pathophysiological mechanisms at play.
Hannah Zhang, N. Dhalla
semanticscholar   +1 more source

Review article: pathogenesis and clinical manifestations of gastrointestinal involvement in systemic sclerosis. [PDF]

, 2017
BACKGROUND: Gastrointestinal tract (GIT) involvement is a common cause of debilitating symptoms in patients with systemic sclerosis (SSc). There are no disease modifying therapies for this condition and the treatment remains symptomatic, largely owing to
Abraham, Assandri, Assassi, Auluck, Bacher, Baron, Baron, Bodukam, Cavazzana, Chizzolini, Chizzolini, Ciechomska, Clark, Cohen, Colina, Crowell, Denton, Denton, Derk, Derynck, Emmanuel, Frech, Fynne, Gabrielli, Goldblatt, Gregersen, Gu, Hartleb, Heyt, Hinz, Hu, Hudson, Hung, Ingraham, Jimenez, Johnson, Jung, Kaburaki, Kaneko, Khanna, Khanna, Koh, Krause, Kumar, Luciano, Malandrini, Manetti, Manetti, Manetti, Marie, Marie, Marie, Marie, Marie, Matucci-Cerinic, Maurer, Miao, Milette, Murray-Lyon, Nagaraja, O'Reilly, O'Reilly, Omair, Parker, Parodi, Pattanaik, Peng, Piasecki, Poelman, Radic, Raja, Raja, Raja, Rajapakse, Reynolds, Richard, Richardson, Rigamonti, Riviere, Roulis, Russell, Sakkas, Savarino, Savarino, Shawis, Singh, Singh, Sjogren, Skare, Solis-Herruzo, Spiegel, Steen, Stern, Stumpf, Thonhofer, Thoua, Trezza, Trojanowska, Valenzuela, Varga, Veale, Vischio, Watson, Wipff, Wynn, Zheng   +105 more
core   +2 more sources

Long-term efficacy of an inactivated H5N1 whole-particle influenza vaccine in nonhuman primates

npj Vaccines
Outbreaks of H5 highly pathogenic avian influenza A viruses (HPAIVs) in animals pose a threat to humans immunologically naïve to avian influenza viruses.
Misako Nakayama, Naoko Kitagawa, Cong Thanh Nguyen, Takako Sasamura, Kyoko Takashima, Hirohito Ishigaki, Hideaki Ishida, Saori Suzuki, Yoshihiro Sakoda, Mai Quynh Le, Hiroshi Kida, Kazumasa Ogasawara, Yasushi Itoh   +12 more
doaj   +1 more source

PTGER4 expression-modulating polymorphisms in the 5p13.1 region predispose to Crohn's disease and affect NF-κB and XBP1 binding sites. [PDF]

, 2012
Genome-wide association studies identified a PTGER4 expression-modulating region on chromosome 5p13.1 as Crohn's disease (CD) susceptibility region. The study aim was to test this association in a large cohort of patients with inflammatory bowel disease (
Achkar, Jean-Paul, Balschun, Tobias, Brand, Stephan, Czamara, Darina, Diegelmann, Julia, Duerr, Richard H., Franke, Andre, Glas, Jürgen, Kamboh, M. Ilyas, Müller-Myhsok, Bertram, Olszak, Torsten, Pasciuto, Giulia, Seiderer, Julia, Wetzke, Martin, Wolf, Christiane   +14 more
core   +4 more sources

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Th17, intestinal microbiota and the abnormal immune response in the pathogenesis of celiac disease [PDF]

, 2015
Celiac disease (CD) is an autoimmune enteropathy induced by the ingestion of gluten in genetically predisposed individuals who carry the HLA-DQ2 or -DQ8 alleles.
Cicerone, Clelia, Nenna, Raffaella, Pontone, Stefano   +2 more
core  

Principles of Periodontology [PDF]

, 2013
Periodontal diseases are among the most common diseases affecting humans. Dental biofilm is a contributor to the etiology of most periodontal diseases.
Aas, Africa, Agrawal, Albandar, Albandar, Albandar, Albandar, Albandar, Albandar, Allen, Ambrosini, American Academy of Periodontology, American Academy of Periodontology, American Academy of Periodontology, American Academy of Periodontology, American Academy of Periodontology, American Academy of Periodontology, American Academy of Periodontology, American Academy of Periodontology, American Academy of Periodontology, American Academy of Periodontology, American Academy of Periodontology, Andersen, Andia, Apatzidou, Apatzidou, Aranki, Arendorf, Armitage, Armitage, Arno, Attström, Axelsson, Axelsson, Axelsson, Axelsson, Axelsson, Axelsson, Badersten, Badersten, Badersten, Baehni, Baelum, Baelum, Baer, Barbour, Bassler, Becker, Bergström, Beuchat, Billings, Bonito, Borrell, Bostanci, Bowers, Bowers, Brayer, Brett, Brewer, Brill, Buchanan, Caffesse, Carranza, Caton, Cecil, Centers for Disease Control and Prevention, Cercek, Chambrone, Chapple, Chapple, Choi, Christou, Chung, Cianciola, Claffey, Claffey, Clark, Clarridge, Clementini, Cobb, Cohen, Collet-Schaub, Corbet, Corey, Cortellini, Cortellini, Cosyn, Cosyn, Crane, Crespi, Czarnetzki, Dale, Darré, Dasanayake, Davé, de Almeida, De Iudicibus, De Lissovoy, De Stefano, Dentino, DeRouen, DeVore, Dolan, Donnenfeld, Dragoo, Drisko, D’Aiuto, Egelberg, Eickholz, Emrich, Erley, Esposito, Fauchard, Ferreira, Fine, Fleischer, Flemmig, Fourrier, Friedman, Galicia, Gasche, Gaunt, Giannobile, Giannobile, Glick, Glickman, Gold, Gold, Golub, Gore, Gottlow, Gottlow, Greenstein, Griffiths, Grob, Grossi, Grossi, Grossi, Guerini, Gürsoy, Haffajee, Haffajee, Hamp, Hanes, Hart, Haslam, Hassell, Hasturk, Haubek, Haubek, Hedley, Hefti, Heijl, Heitz-Mayfield, Heitz-Mayfield, Helldén, Henderson, Henke, Hiatt, Higashi, Hinrichs, Hirschfeld, Holm, Holman, Holt, Holt, Hornef, Hugoson, Hugoson, Hujoel, Hujoel, Hujoel, Hujoel, Hujoel, Hujoel, Hunter, Inagaki, Janket, Jeffcoat, Jenkins, Jepsen, Jin, Johnson, Jori, Joss, Kaldahl, Kaldahl, Kaldahl, Kanzler, Kao, Karpinia, Kato, Kawai, Kenney, Kenney, Kenney, Kiger, Kigure, Kilian, Kim, Kinane, Kirkwood, Kirkwood, Kitano, Knöfler, Kolenbrander, Kolenbrander, Kornman, Kornman, Kressin, Krisanaprakornkrit, Kroes, Kumar, Kuramitsu, Kwok, Laine, Lalla, Lamell, Lang, Lang, Lang, Lang, Laskaris, Lebel, Lesaffre, Liese, Linden, Lindhe, Listgarten, Liu, Loesche, Loomer, Loos, Loscalzo, Luepke, Lynch, Lynch, Löe, Löe, Löe, Löe, Löe, Madianos, Magnusson, Mah, Mahanonda, Maier, Manson, Marazita, Mariotti, Mariotti, Mariotti, Marsh, Marshall, Martinez-Canut, Matia, Mattila, Matuliene, Melcher, Mellonig, Mendez, Merchant, Merritt, Merritt, Meyer, Michalowicz, Michalowicz, Michalowicz, Miller, Miller, Miller, Mombelli, Mongardini, Moore, Mucci, Murayama, Murphy, National Center for Health Statistics, Needleman, Needleman, Nelson, Nesse, Nicholson, Nishida, Novak, Nyman, Nørskov-Lauritsen, Ochsenbein, Offenbacher, Offenbacher, Offenbacher, Offenbacher, Offenbacher, Padbury, Page, Page, Page, Page, Page, Page, Page, Palmer, Paquette, Paster, Paster, Patton, Petersen, Pihlstrom, Pihlstrom, Pischon, Polimeni, Pontoriero, Pontoriero, Porter, Preber, Preber, Preshaw, Preshaw, Preshaw, Quirynen, Ramfjord, Rams, Ranney, Reddy, Reddy, Reimann, Renvert, Reynolds, Roberts, Robinson, Rosenow, Ross, Ross, Röthlisberger, Sabet, Saito, Sanz, Saxén, Saxén, Scannapieco, Scannapieco, Scannapieco, Schallhorn, Schallhorn, Schluger, Schmidlin, Schroeder, Schroeder, Schwarz, Sculean, Sculean, Seinost, Sepe, Serino, Seymour, Seymour, Shklar, Shklar, Sicilia, Silness, Simonka, Skudutyte-Rysstad, Slots, Socransky, Socransky, Socransky, Socransky, Socransky, Stahl, Stahl, Stahl, Stambaugh, Stamm, Stavropoulos, Stefanac, Summers, Suntharalingam, Suzuki, Syriänen, Söderholm, Söderholm, Taichman, Takeuchi-Hatanaka, Tanner, Tanner, Tanner, Taubman, Taylor, Tervonen, Theilade, Thomas, Timmerman, Tomasi, Tonetti, Tonetti, Tonetti, Tonetti, Tonetti, Tonetti, Trombelli, Tuite-McDonnell, Tunkel, van der Velden, van der Velden, Van der Weijden, van Dyke, van Dyke, van Dyke, Waerhaug, Waite, Walker, Walker, Walker, Walmsley, Wang, Westfelt, Wiebe, Williams, Williams, Wilson, Wilson, Wohlfahrt, Yamazaki, Ylöstalo, Yukna, Yukna, Yukna, Zambon, Zambon   +428 more
core   +2 more sources

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

Intraoral Pressure Differences Between Patients with Dysphagia and Healthy Individuals: A Pilot Study Using a Novel Intraoral Pressure Sensor

Oral
Background: Intraoral pressure contributes significantly to bolus transport during swallowing, along with tongue and pharyngeal pressures. However, conventional assessment methods (e.g., manometry, tongue pressure measurement) have limitations, including
Saki Mizutani, Sachie Nakao, Rikako Sato, Akira Tada, Kota Amano, Mana Oshio, Atsuko Otsuka, Yoko Iwase, Hiroshige Taniguchi   +8 more
doaj   +1 more source

Transcriptomic changes in liver transplant recipients with non-alcoholic steatohepatitis indicate dysregulation of wound healing

Frontiers in Endocrinology, 2023
BackgroundNon-alcoholic steatohepatitis (NASH) has become a leading indication for liver transplantation. However, it often recurs in the graft and can also arise de novo in individuals transplanted for other indications.
Diogo Pellegrina, Khairunnadiya Prayitno, Amirhossein Azhie, Elisa Pasini, Cristina Baciu, Sandra Fischer, Jüri Reimand, Jüri Reimand, Jüri Reimand, Mamatha Bhat, Mamatha Bhat, Mamatha Bhat   +11 more
doaj   +1 more source