Results 281 to 290 of about 1,881,156 (313)
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Pathogenesis of Hirschsprung's disease.
Journal of pediatric surgery, 2000Hirschsprung's disease is an inherited disorder showing incomplete penetrance and variable expressivity. Genetic mapping and mutation screening of candidate genes, together with the study of several natural and knockout animal models, clearly have shown the involvement of several different genes in the pathogenesis of Hirschsprung's disease.
MARTUCCIELLO, GIUSEPPE +3 more
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The pathogenesis of Perthes' disease
The Journal of Bone and Joint Surgery. British volume, 1976It has been shown that in the puppy, two infarcts separated by an interval of four weeks produce a disorder of long duration which results in flattening and broadening of the femoral head and which reproduces the radiological changes seen in Perthes' disease in man. The histological appearances produced by two infarcts are characteristic.
A, Inoue +3 more
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The pathogenesis of coeliac disease
Molecular Aspects of Medicine, 2005Coeliac disease is a common condition and its prevalence in UK is now thought to be approximately 1:100. It is being diagnosed and treated more frequently as awareness at the primary care level has increased. Coeliac disease is a complex disorder and is frequently associated with other disease processes.
Ciclitira, Paul +3 more
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The pathogenesis of Hodgkin's disease
Blood Reviews, 1990Extensive clinical research over the past few decades has changed Hodgkin's disease from a routinely fatal disease to a usually curable disease. However, treatment is far from perfect; a substantial percentage of patients are not cured of their primary disease, and a substantial percentage of patients die of treatment-related second malignancies ...
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Rheumatology International, 1989
The etiology and pathogenesis of Lyme disease are reviewed and the value of the condition as a human model for an infectious etiology of rheumatic disease is discussed. Similarities between Lyme disease and rheumatoid arthritis are considered.
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The etiology and pathogenesis of Lyme disease are reviewed and the value of the condition as a human model for an infectious etiology of rheumatic disease is discussed. Similarities between Lyme disease and rheumatoid arthritis are considered.
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PATHOGENESIS OF HODGKIN'S DISEASE
The Lancet, 1972Abstract A hypothesis, based on clinical and laboratory observations, relates viral infection and host immunity to the pathogenesis of Hodgkin's disease. In this hypothesis T cells (thymus- derived lymphocytes) during viral infection undergo antigenic alteration of their surface while normal immunocompetent T cells within the same lymphoid organ react
S E, Order, S, Hellman
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The Pathogenesis of Graves’ Disease
Endocrine Practice, 1995We have hypothesized over many years that Graves' disease (GD) and the other autoimmune thyroid diseases (AITD) are each due to antigen-specific defects in suppressor (regulatory) T lymphocyte function. There have been several reports dealing with the role of regulatory T lymphocyte subsets, ie., that will prevent autoimmune disease in these and other ...
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The pathogenesis of autoimmune diseases
Scandinavian Journal of Clinical and Laboratory Investigation, 2001Autoimmunopathies are chronic inflammatory diseases which can be subdivided into several specificities on the ground of the clinical picture as well as serological findings and involvement of organ systems like the kidney, central nervous system or the hematopoietic system. The pathogenesis of these diseases is incompletely understood.
H M, Lorenz, M, Herrmann, J R, Kalden
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The pathogenesis of Hirschsprung disease
Current Opinion in Gastroenterology, 2002Hirschsprung disease is the most common congenital malformation of the enteric nervous system. Phenotypic expression is variable because of incomplete penetrance, and the pathogenesis is multifactorial. Although mutations of the RET tyrosine kinase gene remain the most commonly identified cause, there are now eight separate human gene loci identified ...
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The pathogenesis of celiac disease
Gastroenterology, 1998A, Godkin, D, Jewell
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