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The Pathogenesis of Crohn’s Disease
Digestion, 2001Although much progress has been made in understanding the pathogenesis of Crohn’s disease, the precise etiology of Crohn’s disease still remains unknown. In our serial studies on Crohn’s disease, we found a decrease in NK and ADCC activities as well as a decrease in the phagocytic activity by monocytes, whereas an increased superoxide production ...
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The pathogenesis of coeliac disease
The International Journal of Biochemistry & Cell Biology, 2004Coeliac disease is a chronic enteropathy caused by intolerance to gluten proteins. The true prevalence of this condition is greater than previously thought, with increasing numbers of 'silent' cases being diagnosed. Untreated coeliac disease is associated with significant morbidity and increased mortality.
Dewar, D, Pereira, S P, Ciclitira, P J
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Pathogenesis of Parkinson's Disease
Archives of Neurology, 1982Nucleolar volume and melanin pigment were measured in nerve cells of the substantia nigra in cases of idiopathic Parkinson's disease and in other cases of parkinsonism associated with cerebrovascular disease. In cerebrovascular parkinsonism, nucleolar volume is reduced by 16%, whereas melanin content is unchanged, reflecting local deficiencies in ...
D M, Mann, P O, Yates
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The Pathogenesis of Lyme Disease
Rheumatic Disease Clinics of North America, 1989Lyme disease affects several major organ systems and leads to chronic illness. The pathogenesis of this disease appears to be centered around the long-term persistence of the organisms in tissues. In Lyme disease, isolations of B. burgdorferi are rare.
J C, Garcia-Monco, J L, Benach
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Castleman Disease Pathogenesis
Hematology/Oncology Clinics of North America, 2018Castleman disease (CD) describes a group of heterogeneous disorders with common lymph node histopathologic features, including atrophic or hyperplastic germinal centers, prominent follicular dendritic cells, hypervascularization, polyclonal lymphoproliferation, and/or polytypic plasmacytosis.
David C, Fajgenbaum, Dustin, Shilling
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THE PATHOGENESIS OF GRAVES' DISEASE
Endocrinology and Metabolism Clinics of North America, 1998Graves' disease, one of the autoimmune thyroid diseases, is caused by the production of IgG autoantibodies directed against the thyrotropin receptor. These antibodies bind to and activate the receptor, causing the autonomous production of thyroid hormones.
B, McIver, J C, Morris
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The pathogenesis of autoimmune disease
Immunology Today, 1992The mechanisms of autoimmune pathology are normally described on a disease-by-disease basis. Taking a novel angle, Peter Gergely here examines the role of different types of leucocytes across a spectrum of autoimmune diseases, combining the results from a number of Hungarian laboratories.
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Pathogenesis of prion diseases
Acta Neuropathologica, 2005Prion diseases are rare neurological disorders that may be of genetic or infectious origin, but most frequently occur sporadically in humans. Their outcome is invariably fatal. As the responsible pathogen, prions have been implicated. Prions are considered to be infectious particles that represent mainly, if not solely, an abnormal, protease-resistant ...
Ursula, Unterberger +2 more
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Periodontal Diseases: Pathogenesis
Annals of Periodontology, 1996Question Set 1. What are the important destructive mechanisms in periodontal diseases? 2. What are the important protective mechanisms in periodontal diseases? 3. What are the important genetic factors and what is the state-of-the art relative to assessing these genetic factors in periodontal diseases? 4.
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Pathogenesis of Meniere’s Disease
Journal of Vestibular Research, 1990While endolymphatic hydrops is a characteristic pathologic feature of Menière's disease, there are exceptions to this rule. There is evidence that hydrops develops as a result of malabsorption of endolymph. This implies dysfunction of the endolymphatic sac and duct, which normally absorb endolymph.
M M, Paparella, B P, Kimberley
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