Results 201 to 210 of about 9,212,440 (297)

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Population-Based Big Data Analysis on Disease Patterns in Patients Identified With Juvenile Idiopathic Arthritis Using National Claims Data. [PDF]

J Korean Med Sci
Min EJ, Lee SH, Jo JY, Ahn JG, Jeong DC.
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Pathological patterns of biliary disease [PDF]

Clinical Liver Disease, 2017
openaire   +2 more sources

Characterization of Disease Patterns in Children with Intracranial Abscesses for Enhanced Clinical Decision-Making. [PDF]

Pediatr Rep
Middelkamp M, Kania MM, Groth FS, Ricklefs FL, Dührsen L.   +4 more
europepmc   +1 more source

Take-all disease patterns in fields

, 1993
Bateman, G. L., Hornby, D.
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Breast Disease Patterns Among Patients Presenting for Mammography in a Major Hospital in the Volta Region of Ghana: A Five-Year Descriptive Retrospective Study. [PDF]

Int J Breast Cancer
Angmorterh SK, Benjamin MB, Oppong RK, Agyemang PN, Angaag NA, Kekessie KK, van de Venter R, Nsor-Atindana J, Yarfi C, Angmorterh PM, Aboagye S, Amoussou-Gohoungo MM, Inusah A, Dzefi-Tettey K, Kortei NK.   +14 more
europepmc   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

The compositional and functional imbalance of the gut microbiota in CKD linked to disease patterns. [PDF]

J Transl Med
Li J, Shen Y, Yan K, Wang S, Jiao J, Chi H, Zhong JC, Dong Y, Wang P.   +8 more
europepmc   +1 more source