Results 271 to 280 of about 12,789,497 (387)

Low air-temperatures exposure as a risk factor for coronary artery disease progression - personalized analysis. [PDF]

open access: yesBMC Cardiovasc Disord
Urbanowicz T   +13 more
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Association of Autonomic Dysfunction With Disease Progression and Survival in Parkinson Disease

open access: yesJAMA Neurology, 2017
E. de Pablo-Fernández   +5 more
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

A blood-based DNA damage signature in patients with Parkinson's disease is associated with disease progression. [PDF]

open access: yesNat Aging
Sproviero D   +10 more
europepmc   +1 more source

Serum concentration of intercellular adhesion molecule–1 in patients with hepatocellular carcinoma is a marker of the disease progression and prognosis [PDF]

open access: bronze, 1995
Yukihiro Shimizu   +7 more
openalex   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

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