Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare
Advanced Science, EarlyView.Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu +10 more
wiley +1 more source
Monocytes and immune evasion strategies in HIV: Unraveling the intricacies. [PDF]
Medicine (Baltimore)Obeagu EI, Obeagu GU.
europepmc +1 more source
Advanced Science, EarlyView.Urinary Fusobacterium nucleatum–derived outer membrane vesicles are shown to promote bladder cancer lymphatic metastasis. The vesicle protein FomA activates TLR2/NF‐κB signaling in tumor cells, induces IL‐6 secretion, and drives M2b macrophage polarization and VEGF‐C–dependent lymphangiogenesis, revealing a microbiota‐driven mechanism linking tumor ...
Wentai Shangguan +17 more
wiley +1 more source
Clinical significance of a possible route of transmission of <i>Candida</i> and <i>Helicobacter pylori</i> associations in gastroduodenal pathology. [PDF]
World J Gastrointest PathophysiolKotelevets SM.
europepmc +1 more source
Deciphering the Impact of RAC1‐SPTAN1 in ARPKD Cystogenesis Using Multifaceted Models
Advanced Science, EarlyView.Distal/connecting tubules expressing SLC8A1 have been suggested as a potential origin of ARPKD cysts. SPTAN1 has been identified as a key molecule in ARPKD cyst formation. Restoring SPTAN1 in PKHD1−/− organoids reduced cyst formation, normalized calcium levels, and decreased RAC1/c‐FOS expression, highlighting SPTAN1's role in ARPKD and the potential ...
Shohei Kuraoka +9 more
wiley +1 more source
mGem: Deciphering how polyomaviruses coexist with their hosts for a lifetime. [PDF]
mBioPipas JM, Sullivan CS.
europepmc +1 more source
Advanced Science, EarlyView.ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley +1 more source
Aquatic Animal Viruses and Antiviral Immunity: A Closing Editorial. [PDF]
VirusesPolinski MP.
europepmc +1 more source
Multi‐Functional Adaptive Interfaces for Next‐Generation Wearable and Implantable Bioelectronics
Advanced Science, EarlyView.Adaptive Biointerfaces: A comprehensive overview of next‐generation bioelectronics is presented, highlighting mechano‐adaptive and biophysiologically adaptive interfaces that enable stable, long‐term integration with living tissues. As illustrated in the image, adaptive interface strategies, including mechano‐adaptivity (e.g., injectability, shape ...
Jinhong Park +7 more
wiley +1 more source
To Kill a Macrophage: Targeted Strategies to Eliminate Macrophage Reservoirs of HIV. [PDF]
VirusesRikard-Bell L +4 more
europepmc +1 more source