Results 61 to 70 of about 205,176 (281)

Bats as reservoirs of severe emerging infectious diseases

Virus Research, 2015
(Uploaded by Plazi for the Bat Literature Project) In recent years severe infectious diseases have been constantly emerging, causing panic in the world. Now we know that many of these terrible diseases are caused by viruses originated from bats (Table 1), such as Ebola virus, Marburg, SARS coronavirus (SARS-CoV), MERS coronavirus (MERS-CoV), Nipah ...
Han, Hui-Ju, Wen, Hong-ling, Zhou, Chuan-Min, Chen, Fang-Fang, Luo, Li-Mei, Liu, Jian-wei, Yu, Xue-Jie   +6 more
openaire   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The non-human reservoirs of Ross River virus: a systematic review of the evidence

Parasites & Vectors, 2018
Understanding the non-human reservoirs of zoonotic pathogens is critical for effective disease control, but identifying the relative contributions of the various reservoirs of multi-host pathogens is challenging.
Eloise B. Stephenson, Alison J. Peel, Simon A. Reid, Cassie C. Jansen, Hamish McCallum   +4 more
doaj   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Diverse tick-borne microorganisms identified in free-living ungulates in Slovakia [PDF]

, 2018
Background: Free-living ungulates are hosts of ixodid ticks and reservoirs of tick-borne microorganisms in central Europe and many regions around the world.
A Alberti, A Mysterud, A Nahayo, A Obiegala, A Ohlson, A Ortuňo, A Pereira, A Pereira, A Rizzoli, A Zintl, AO Michel, AS Faria, B Flaisz, B Skotarczak, B Víchová, BL Herwaldt, C Billinis, C Huhn, C Kiffner, C Kiffner, C Martin, C Silaghi, C Silaghi, C Silaghi, CA Becker, D Duh, D González-Barrio, D Hulinska, D Hulínská, D Žele, E Dorko, E Overzier, E Overzier, E Špitalská, E Špitalská, Elena Kocianová, Eva Špitalská, F Strle, F Veronesi, FCA Pacilly, H Polin, H Sprong, H Sprong, H-P Fuehrer, Hein Sprong, HK Hinaidy, HS Ginsberg, I Baráková, I Baráková, J García-Sanmartín, J Gray, J Hapunik, J Michalik, J Michalik, J Nosek, J Stańczak, J Řeháček, J Řeháček, JM Medlock, JM Rijks, JS Liz, JW Courtney, K Häselbarth, K Kurtenbach, K Reiterová, K Siuda, K Stefanidesova, K Strasek Smrdel, K Tamura, K Štefanidesová, KT Friedhoff, L Berthová, L Gilbert, L Lempereur, L Lempereur, L Malandrin, L Minichová, L Qviller, L Tomassone, Lenka Mahríková, Lenka Minichová, Leonhard Schnittger, M Adamska, M Battilani, M Derdáková, M Di Domenico, M Jouglin, M Kauffmann, M Kazimírová, M Maurin, M Petrovec, M Petrovec, M Pfäffle, M Salman, M Sawczuk, M Sawczuk, Manoj Fonville, MJ Yabsley, MO Andersson, MP Tampieri, Mária Kazimírová, N Saitou, NS Alexander, O Rosef, P Heyman, P Zeman, R Cézanne, R Galuppi, R Welc-Falęciak, Radoslav Caban, RC Galindo, RF Massung, RL Regnery, S Casati, S Hornok, S Hornok, S Hornok, S Jahfari, S Jahfari, S Kumar, S Schorn, S Stuen, S Stuen, S Stuen, S Zanet, SE Randolph, SE Randolph, T Dugat, T Dugat, T Kiss, T Vor, TR Hofmeester, U Mackenstedt, V Tagliapietra, V Černý, VV Ebani, VV Ebani, VV Ebani, VV Ebani, W Scharf, Z Hamšíková, Z Hamšíková, Z Hamšíková Svitálková, Z Woldehiwet, Zuzana Hamšíková, Ø Hammer, Ø Øines   +146 more
core   +4 more sources

Genetic structure and evolution of the Leishmania genus in Africa and Eurasia: what does MLSA tell us [PDF]

, 2013
Leishmaniasis is a complex parasitic disease from a taxonomic, clinical and epidemiological point of view. The role of genetic exchanges has been questioned for over twenty years and their recent experimental demonstration along with the identification ...
Berry, Vincent, Brisse, Sylvain, Chevenet, François, Diancourt, Laure, El Baidouri, Fouad, Marty, Pierre, Pratlong, Francine, Ravel, Christophe   +7 more
core   +4 more sources

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Development of an Amplicon-Based Next-Generation Sequencing Protocol to Identify Leishmania Species and Other Trypanosomatids in Leishmaniasis Endemic Areas

Microbiology Spectrum, 2021
Trypanosomatid infections are an important public health threat affecting many low-income countries across the tropics, particularly in the Americas. Trypanosomatids can infect many vertebrate, invertebrate, and plant species and play an important role ...
Luz H. Patiño, Adriana C. Castillo-Castañeda, Marina Muñoz, Jesus E. Jaimes, Nicolas Luna-Niño, Carolina Hernández, Martha S. Ayala, Patricia Fuya, Claudia Mendez, Carlos E. Hernández-Pereira, Lourdes Delgado, Claudia M. Sandoval-Ramírez, Plutarco Urbano, Alberto Paniz-Mondolfi, Juan David Ramírez   +14 more
doaj   +1 more source

Integral chain management of wildlife diseases [PDF]

, 2019
The chytrid fungus Batrachochytrium dendrobatidis has caused the most prominent loss of vertebrate diversity ever recorded, which peaked in the 1980s. Recent incursion by its sister species B. salamandrivorans in Europe raised the alarm for a new wave of
Canessa, Stefano, Carbonell, Francesc, Carranza, Salvador, Casanovas, Ricard, Chiers, Koen, Fernandez-Giberteau, Daniel, Ferran, Albert, Guinart, Daniel, Kelly, Moira, Li, Zhimin, Martel, An, Martinez-Martinez, Diego, Martinez-Silvestre, Albert, Molina, Carolina, Obon, Elena, Pagone, Viviana, Pannon, Pep, Pasmans, Frank, Perez-Sorribes, Laia, Picart, Mariona, Piulats, Dolors, Tarrago-Guarro, Aida, Van Praet, Sarah, Velarde-Nieto, Roser, Vila-Escale, Mireia   +24 more
core   +2 more sources