Results 241 to 250 of about 2,698,914 (384)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Studies on the Pathologic Physiology of Pulmonary Hypertension in Mitral Valvular Disease : Part 1. The Role of Sympathetic Nervous System on the Increment of Pulmonary Vascular Resistance

, 1969
Yutaka Yoshida
openalex   +2 more sources

MIF as an oncogenic driver of low‐heterogeneity melanomas

Molecular Oncology, EarlyView.
Shvefel and colleagues identified tumor‐secreted macrophage migration inhibitory factor (MIF) as an upregulated cytokine that mediates immune resistance in melanomas with low‐intratumoral heterogeneity. MIF and its functional paralogue D‐dopachrome tautomerase (D‐DT or MIF‐2) have overlapping but nonidentical signaling functions and are hypothesized to
Thuy T. Tran, Gabriela Athziri Sánchez‐Zuno, Rajan P. Kulkarni, Harriet M. Kluger, Richard Bucala   +4 more
wiley   +1 more source

Alternaria alternata effector AaAlta1 targets CmWD40 and participates in regulating disease resistance in Chrysanthemum morifolium. [PDF]

PLoS Pathog
Zhang S, Liu L, Li W, Yin M, Hu Q, Chen S, Chen F, Liu Y, Guan Z, Jiang J.   +9 more
europepmc   +1 more source

INVESTIGATION OF DISEASE RESISTANCE AND THE MATHEMATICAL PROBLEM OF PATTERNS

, 1961
Roger J. Williams
openalex   +1 more source

An age‐related resistance of chickens to Marek's disease: Some preliminary observations [PDF]

, 1973
R. L. Witter, J. Μ. Sharma, J. J. Solomon, L.R. Champion   +3 more
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Using genome-wide associations and host-by-pathogen predictions to identify allelic interactions that control disease resistance. [PDF]

Plant Genome
Hudson O, Brawner J.
europepmc   +1 more source

INHERITANCE OF RESISTANCE TO BLACK ROOT-ROT DISEASE IN TOBACCO. : I. Analysis of the Gene Controlling the Resistance.

, 1968
Akio Nakamura, Toshio Matsuda, Hiroshi Nakatogawa   +2 more
openalex   +2 more sources

Unusual resistance to ionizing radiation of the viruses of kuru, Creutzfeldt-Jakob disease, and scrapie [PDF]

, 1979

openalex   +1 more source