Results 231 to 240 of about 8,489,060 (313)

Reply: neutral transcriptome rewiring promotes quantitative disease resistance evolvability at the species level. [PDF]

Plant Cell
Delplace F, Khafif M, Barbacci A, Stam R, Raffaele S.   +4 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Microbiome analysis and epigenetic patterns revealed distinct differences between two elm species with contrasting Dutch elm disease resistance. [PDF]

Microbiome
Hoenicka H, Ulrich K, Haffner C, Starczak M, Gackowski D, Bubner B, Ulrich A.   +6 more
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Harnessing indigenous bacterial defenders to improve disease resistance and plant health in vegetable <i>Brassica</i> crops. [PDF]

Sustain Microbiol
Madakaripura Rangaswamy GG, Pasupuleti S, Umfuyisoni J, Chapman TA, Plett JM, Nielsen UN.   +5 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Expanding the disease-resistance gene repertoire for sunflower breeding through pan-genomic insights

Vazquez MT, Contreras-Moreira B, Lia V, Paniego N, Filippi CV.   +4 more
europepmc   +1 more source

WheatRPred: deep learning framework for predicting disease resistance protein in wheat and its wild relatives. [PDF]

J Genet Eng Biotechnol
Pandey B, Singh M, Mishra AK.
europepmc   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

The barley disease resistance protein <i>AvrPphB Response 1</i> exhibits nucleocytoplasmic localization. [PDF]

MicroPubl Biol
Helm M, Myers A, Kelly R, Jaiswal N, Iyer-Pascuzzi A, Scofield S.   +5 more
europepmc   +1 more source