Results 251 to 260 of about 2,698,914 (384)

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

The Relation between the Host Resistance and the Disease Type in Mouse Leprosy

, 1962
Yoichiro Kawaguchi
openalex   +4 more sources

Bat genomes illuminate adaptations to viral tolerance and disease resistance. [PDF]

Nature
Morales AE, Dong Y, Brown T, Baid K, Kontopoulos D-, Gonzalez V, Huang Z, Ahmed AW, Bhuinya A, Hilgers L, Winkler S, Hughes G, Li X, Lu P, Yang Y, Kirilenko BM, Devanna P, Lama TM, Nissan Y, Pippel M, Dávalos LM, Vernes SC, Puechmaille SJ, Rossiter SJ, Yovel Y, Prescott JB, Kurth A, Ray DA, Lim BK, Myers E, Teeling EC, Banerjee A, Irving AT, Hiller M.   +33 more
europepmc   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Investigating a novel β-glucan source to enhance disease resistance in Pacific white shrimp (Penaeus vannamei). [PDF]

Sci Rep
Uengwetwanit T, Uawisetwathana U, Angthong P, Phanthura M, Phromson M, Tala S, Thepsuwan T, Chaiyapechara S, Prathumpai W, Rungrassamee W.   +9 more
europepmc   +1 more source

Resistance to fatal central nervous system disease by mouse hepatitis virus, strain JHM [PDF]

, 1978
Stephen A. Stohlman, Jeffrey A. Frelinger   +1 more
openalex   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

All Roads Lead to Rome: Pathways to Engineering Disease Resistance in Plants. [PDF]

Adv Sci (Weinh)
Ikram AU, Khan MSS, Islam F, Ahmed S, Ling T, Feng F, Sun Z, Chen H, Chen J.   +8 more
europepmc   +1 more source

Degree of Splenomegaly in Domestic Chickens Selected for Resistance and Susceptibility to Marek’s Disease

, 1969
J. R. Morris, F.N. Jerome, B.S. Reinhart
openalex   +1 more source

Absence of age-resistance in neonatally thymectomised chickens as evidence for cell-mediated immune surveillance in Marek's disease [PDF]

, 1975
J. Μ. Sharma, R. L. Witter, H. G. Purchase   +2 more
openalex   +1 more source