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Genetic susceptibility to Alzheimer disease
Trends in Genetics, 1995Alzheimer disease (AD) is the leading cause of dementia in the elderly. Less than a decade ago, it was questioned as to whether or not genes were even involved in anything but rare early onset AD. Since that time, using a variety of genetic epidemiological and molecular biological techniques, four loci have been identified that play a role in the ...
M A, Pericak-Vance, J L, Haines
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Cytokine genes and disease susceptibility
Cytokine, 2004Complex networks of cytokines interact in a dynamic way to homeostatically regulate immune responses and other biological pathways. It is, therefore, not surprising that variation in cytokine level has been correlated with disease susceptibility and process.
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The Genetics of Graves’ Disease: HLA and Disease Susceptibility*
The Journal of Clinical Endocrinology & Metabolism, 1985To relate genetic variation in Graves' disease (GD) susceptibility to polymorphism at MHC loci, clinical and family studies were undertaken in eastern Hungary. Among 1980 relatives of 534 index patients, 2.9% of siblings, 2.7% of offspring, and 3.0% of parents had GD.
V, Stenszky +5 more
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Human Susceptibility to Legionnaires’ Disease
2012Legionella pneumophila is a facultative intracellular pathogen that is an important cause of pneumonia. Although host factors that may predispose to acquisition of Legionnaire's Disease (LD) include comorbid illnesses (e.g., diabetes, chronic lung disease), age, male sex, and smoking, many individuals have no identifiable risk factors.
William R, Berrington, Thomas R, Hawn
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Relationship Between the ABO Blood Group and the Coronavirus Disease 2019 (COVID-19) Susceptibility
Clinical Infectious Diseases, 2021Dongfeng Gu +2 more
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Genetic susceptibility to infectious diseases
The Pediatric Infectious Disease Journal, 2003David, Burgner, Michael, Levin
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Two novel STAT1 mutations cause Mendelian susceptibility to mycobacterial disease
Biochemical and Biophysical Research Communications, 2022Meiqi Hou, Xianqin Zhang
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Susceptibility to Infectious Diseases
2003In the last fifteen years, substantial progress has been made in identifying why some people are particularly susceptible to specific infectious diseases. Extensive evidence has accumulated that host genes are important determinants of the outcome of infection for many common pathogens. This book summarises advances that have been made in understanding
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