Results 131 to 140 of about 348,589 (256)
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
ParasitologiaClonorchis sinensis and Metagonimus spp. are prevalent parasites in Korea, and accurate diagnosis is essential because treatment dosages differ between infections.
Hee-Eun Shin +7 more
doaj +1 more source
Small irrigation tanks as a source of malaria mosquito vectors: a study in north-central Sri Lanka [PDF]
Watersheds / Tank irrigation / Rehabilitation / Malaria / Waterborne diseases / Disease vectors / Sri Lanka / Yan ...
Amerasinghe, F. P. +6 more
core
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
A Novel Approach to Monitoring Scorpion Sting Trends in Qeshm County Over a Five-Year Period (2019–2024) [PDF]
Journal of Mazandaran University of Medical SciencesBackground and purpose: Scorpion stings are considered a significant public health issue in many countries, including Iran. With the increasing incidence of scorpion stings in Qeshm County, this study aimed to provide a comprehensive assessment of ...
Hassan Nasirian +5 more
doaj
Royal Society Open ScienceVector-borne diseases (VBDs) pose significant global health threats, particularly in tropical and subtropical regions. Remote sensing (RS) and geospatial technologies offer valuable tools for monitoring environmental changes and predicting disease ...
Ebrahim Abbasi
doaj +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
MicroorganismsThis study investigated the prevalence of Anaplasma and Ehrlichia in 494 engorged ticks collected from various animal hosts, including cattle, horses, sheep, chickens, dogs, and cats, in six regions of northern Kyrgyzstan.
Yu Jung Kim +6 more
doaj +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source