Results 91 to 100 of about 12,576,478 (338)
Communicable Diseases and the Workplace [PDF]
, 2019 [Excerpt] Coming to work when we are sick raises some interesting questions: How contagious are we? Should we stay home? What could be done to prevent disease transmission to others, with its effects on absenteeism, performance, and efficiency, as well ...
Brown, Nellie J
core +1 more source
Perinatal Gene Transfer to the Liver [PDF]
, 2011 The liver acts as a host to many functions hence raising the possibility that any one may be compromised by a single gene defect. Inherited or de novo mutations in these genes may result in relatively mild diseases or be so devastating that death within
Buckley, SM +6 more
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Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
International Journal of Clinical Practice, 1969 George Frederic Still (1868‐1941) was one of 12 children, three of whom died in their first year of life and two later in childhood. He was brought up in Highbury, London. He obtained a scholarship to Merchant Taylor's School and then a further scholarship to Caius College, Cambridge, where he achieved a first class honours in the Classical Tripos.
openaire +6 more sources
Implementation of the pulse rhythmic rate for the efficient diagnosing of the heartbeat
Healthcare Technology Letters, 2019 The mortality rate has risen due to the increase in number of cardiac patients in recent times due to the lack of unawareness of the symptoms. This work mainly aims to detect the anomalies of the rhythmic conditions of the pulse derived from the ...
Visvam Devadoss Ambeth Kumar +6 more
doaj +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source
The American Journal of the Medical Sciences6th American from the fifth and revised London edition. ; xix, [33]-694 p.
openaire +4 more sources
Surveillance and response systems for elimination of tropical diseases : summary of a thematic series in infectious diseases of poverty [PDF]
, 2016 The peer-reviewed journal Infectious Diseases of Poverty provides a new platform to engage with, and disseminate in an open-access format, science outside traditional disciplinary boundaries.
Bergquist, Robert +5 more
core +3 more sources
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source