Results 141 to 150 of about 8,418,710 (310)
We present the valuable contribution of the Arab written sources through its great authors versed in medicine for the knowledge of bioanthropological research. Although many works of medicine generated during the classic period of Islam are not preserved,
Bruno Franco Moreno
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Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Tickborne diseases of the United States : a reference manual for health care providers. Fouth edition, 2017 [PDF]
Based on \u201cTickborne Diseases in Massachusetts: A Physician\u2019s Reference Manual\u201d, produced by collaboration between MDPH, Nancy Shadick, MD, MPH, and Nancy Maher, MPH of the RBB Arthritis and Musculoskeletal Diseases Clinical Research Center
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Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Emerging infectious diseases - staying vigilant tracking emerging infectious diseases
Staying vigilant tracking emerging infectious diseases: CDC\u2019s activities to protect Americans from emerging health threats are a foundation of many critical NCEZID infectious disease programs.
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Working to reduce parasitic diseases in the United States [PDF]
Parasitic diseases not only affect people globally, they also affect many people in the United States. CDC works with partners to reduce parasitic diseases both within the United States and globally by:\u2022 Conducting public health surveillance to ...
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Mosquito-Borne Dog Heartworm Disease
This document provides an overview of mosquito-borne dog heartworm disease, caused by the filarial nematode Dirofilaria immitis. It details the lifecycle of the parasite, which requires both dogs and mosquitoes to develop.
J.k. Nayar, C. Roxanne Connelly
doaj
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
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Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source

