Results 151 to 160 of about 8,590,789 (311)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Recording of orofacial manifestations associated to rare diseases: development of a relational database. [PDF]

Head Face Med
Lima SL, Caldas RA, Amorim MP, Cordeiro JVC, Oelerich O, Daume L, Kleinheinz J, Hanisch M, Bohner L.   +8 more
europepmc   +1 more source

Water-related disease outbreaks surveillance annual summary 1979

Since 1971 the Centers for Disease Control (CDC) has tabulated foodborne and waterborne disease outbreak data separately and reported these data in annual reports.

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Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Participatory Epidemiology of Major Camel Diseases and Their Management in Somalia: The Case of Banadir and Lower Shabelle Regions. [PDF]

Vet Med Int
Salah O, Sh Hassan Y, Yusuf M, AbdiNB H.
europepmc   +1 more source

Graves’ Disease [PDF]

New England Journal of Medicine, 2016
Smith, Terry J, Hegedüs, Laszlo
openaire   +7 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Foodborne Diseases Active Surveillance Network (FoodNet) population survey atlas of exposures; 2006-2007

The Foodborne Diseases Active Surveillance Network (FoodNet) is a collaborative network established in cooperation with the Centers for Disease Control and Prevention\u2019s Emerging Infections Program (EIP); state health departments in California ...

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