Results 201 to 210 of about 22,218,716 (335)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Global perspectives on infectious diseases at risk of escalation and their drivers. [PDF]

Sci Rep
Walker RJ, Kingpriest PT, Gong J, Naisanga M, Ashraf MN, Roberti J, Lang T.   +6 more
europepmc   +1 more source

The Prevention of Early-Onset Group B Streptococcal Infections in the Newborn

Canadian Journal of Infectious Diseases, 1994
Infectious Diseases and Immunization Committee
doaj   +1 more source

Neuromodulation as a Potential Disease-Modifying Therapy for Osteoarthritis

, 2022
Carlos J. Cruz, L. Savannah Dewberry, Kevin J. Otto, Kyle D. Allen   +3 more
openalex   +2 more sources

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

Molecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo, Marco Siringo, Alessandro Vici, Ann Zeuner, Orietta Gandini, Paola Gazzaniga, Chiara Nicolazzo   +6 more
wiley   +1 more source

Risk factors of incident lung diseases and the impact of DMARDs in rheumatoid arthritis patients: a longitudinal study. [PDF]

BMC Pulm Med
Chen G, Zhang Q, Geng L, Zhang Y, Liang J, Jin Z, Qian Z, Xu X, Zhu K, Shu Q, Tang X, Zhang H, Feng X, Chen H, Wang D, Sun L, Shen W.   +16 more
europepmc   +1 more source

Poststreptococcal Arthritis

Canadian Journal of Infectious Diseases, 1995
Infectious Diseases and Immunization Committee
doaj   +1 more source

Epigenetic targets for lung diseases [PDF]

, 2019
Lahousse, Lies
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Addressing psychosocial vulnerability in rare diseases: a call to action from a European expert consensus study. [PDF]

Orphanet J Rare Dis
Smits RM, Aerts A, Angelov T, Bentele M, de Blaauw I, Dellenmark-Blom M, Duijts SFA, Fjermestad K, Franscini M, Grano C, Hendriks S, Inhestern L, Kenny T, von der Lippe C, Oomen L, Rake JP, Rietman AB, van Rooij IALM, Verhaak CM, Voet NBM, Walton H, van Zelst-Stams W, Kwakkenbos L.   +22 more
europepmc   +1 more source