Results 301 to 310 of about 22,218,716 (335)

Analysis of human disease burden, determinants of treatment costs and affordability perceptions in the Rwenzori region, Uganda using DALYs, OLS and Bayesian regression. [PDF]

Cost Eff Resour Alloc
Akugizibwe E, Ndungo I, Mpungu K, Mulinzi S, Karahukayo J.   +4 more
europepmc   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

FEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro, Afshan F. Nawas, Jessica A. Kilgore, Pedro A. S. Nogueira, M.Carmen Lafita‐Navarro, Paul H. Acosta, Roy Garcia, Noelle S. Williams, Maralice Conacci‐Sorrell   +8 more
wiley   +1 more source

Correction: Identification of a novel immature dendritic cell subset with potential pro-leukemic effects in leukemia microenvironment. [PDF]

Cell Death Dis
Cui X, Li Y, Xie W, Li R, Zhang D, Zhang S, Ren Q, Wang L, Zheng G.   +8 more
europepmc   +1 more source

Neuroprotection of low dose carbon monoxide in Parkinson’s disease models commensurate with the reduced risk of Parkinson’s among smokers

K. N. Rose, Musab M. Zorlu, Aline Fassini, Hyowon Lee, Waijiao Cai, Xiaochang Xue, Sung‐Han Lin, Pia Kivisäkk, M. A. Schwarzschild, Xiqun Chen, Stephen N. Gomperts   +10 more
openalex   +1 more source

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Knowledge and beliefs about climate change and emerging infectious diseases in bangladesh: implications for one health approach. [PDF]

J Health Popul Nutr
Rahman MS, Amrin M, Chowdhury AH, Suwanbamrung C, Karamehic-Muratovic A.   +4 more
europepmc   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Metabolites mediate the effects of healthy lifestyles on the risks of common age-related diseases. [PDF]

Front Endocrinol (Lausanne)
Li Y, Li H, Chen X, Liang X.
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Analysis of risk factors for Takotsubo cardiomyopathy in older patients using large-scale medical reimbursement data. [PDF]

Sci Rep
Mizuuchi T, Nojiri S, Urasaki W, Uematsu T, Nishizaki Y, Nagao M, Ishijima M, Aoki S.   +7 more
europepmc   +1 more source