Results 311 to 320 of about 22,218,716 (335)

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

The EMA as a potential driver of competitiveness of orphan medicines in Europe: a focus on regulatory incentives and funding opportunities. [PDF]

Orphanet J Rare Dis
Gomez-Ferreria MA, Garcia-Muñoz V, Zwiers A.   +2 more
europepmc   +1 more source

Cardiac magnetic resonance reveals concealed structural heart disease in patients with frequent premature ventricular contractions and normal echocardiography: A systematic review

Paolo Basile, Nicolò Soldato, Erika Pedio, Paola Siena, Maria Cristina Carella, Ilaria Dentamaro, Yamna Khan, Andrea Baggiano, Saima Mushtaq, Cinzia Forleo, Marco Matteo Ciccone, Gianluca Pontone, Andrea Igoren Guaricci   +12 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Exploring Current Health Policies on Rare Diseases in Greece: A Narrative Review. [PDF]

Int J Pediatr
Tsitsani P, Papamitsou T, Malliarou M, Soteriades ES.   +3 more
europepmc   +1 more source

Prevalence of malnutrition and appropriateness of nutritional support in hospitalized patients: a GLIM-based study. [PDF]

Front Nutr
Deng LM, Liu SP, Long JF, Mo H, Liu M, Liu JY, Zhang YL, Xu DF, Yu HZ, Chen L, Cai H, Yang SB, Xiang M, Liu M, Sun Y, Xie ZJ, Zeng MM, Xie GX.   +17 more
europepmc   +1 more source

Research on the impact of health empowerment on self-management in older patients with chronic disease: based on chain mediating effect analysis. [PDF]

Front Public Health
Wang T, Huang S, Liu J, Liu Y.
europepmc   +1 more source

Enhancing disease clustering through symptom-based analysis and large language model interpretations. [PDF]

Sci Rep
Onojete E, Ibeke E, Ezenkwu CP, Iwendi C, Dhaou IB.   +4 more
europepmc   +1 more source

Corrigendum to: Health insurance in rural Tanzania promotes self-care for among patients with non-communicable diseases via their disease management behaviour. [PDF]

Int Health
europepmc   +1 more source