Results 81 to 90 of about 12,576,478 (338)

Systems biology in inflammatory bowel diseases [PDF]

, 2014
Purpose of review: Ulcerative colitis (UC) and Crohn’s Disease (CD) are the two predominant types of inflammatory bowel disease (IBD), affecting over 1.4 million individuals in the US.
Iliopoulos, D, Koukos, G, Polytarchou, C
core   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

‘Vychegodsky’: a new potato cultivar for the Republic of Komi

Труды по прикладной ботанике, генетике и селекции, 2021
Background. The presented information refers to the completed stage of the breeding process carried out at the Institute of Agrobiotechnologies (Syktyvkar) that led to the development of a new mid-early table potato variety – ‘Vychegodsky’. This cultivar
A. G. Tulinov, A. Yu. Lobanov
doaj   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

A dynamic network approach for the study of human phenotypes [PDF]

, 2009
The use of networks to integrate different genetic, proteomic, and metabolic datasets has been proposed as a viable path toward elucidating the origins of specific diseases.
A Barrat, A Hinks, A Rzhetsky, AB Begovich, AJ Lusis, Albert-László Barabási, C Benesch, CA Hidalgo, CA Hidalgo, César A. Hidalgo, D Lauderdale, DS Lee, GS Cooper, H Goehler, I Feldman, J Hatten, J Kobberling, J Lim, J Zhang, JB Mitchell, JF Rual, K-I Goh, Lauren Ancel Meyers, LI Iezzoni, MA Pujana, MC Oldham, N Craddock, Nicholas A. Christakis, Nicholas Blumm, P McGuffin, P Wordsworth, S Schneeweiss, SE Ahnert, SE Calvano, SF Grant, U Stelzl   +35 more
core   +5 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Occurrence of biotic harmful agents in Czech grass seed production (1995-2004)

Plant Protection Science, 2006
In the years 1995-2004 the spectra of weeds, diseases and pests in grasses grown for seed in the Czech Republic were examined and the effect of external factors on their changes was assessed.
Bohumír Cagaš, Jan Macháč, Jan Frydrych, Radek Macháč   +3 more
doaj   +1 more source

Open questions: Reflections on intrinsically disordered proteins [PDF]

Network Biology, 2021
Intrinsically Disordered Proteins or Regions (IDPs) are proteins that lack a predetermined 3D structure playing key cellular functions including regulation, signaling, and protein-protein/DNA interaction.
Mouna Choura, Ahmed Rebai
doaj  

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Assessing climate change impacts on public health in Haiti: a comprehensive study of disease distribution, modeling, and adaptation strategies

Frontiers in Tropical Diseases
This study examines the relationship between climate change and public health in Haiti, a country already facing socioeconomic challenges. The well-being of Haiti’s vulnerable population is expected to be further affected by climate change, leading to an
Ibrahima Diouf, Ibrahima Sy, Moussa Diakhaté   +2 more
doaj   +1 more source