Results 11 to 20 of about 132,459 (210)
Crohn's disease in monozygotic twins [PDF]
Postgraduate Medical Journal, 1986 Summary A pair of monozygotic twins with Crohn's disease is described. Both have ileocaecal disease and suffered their first symptoms after living apart for 6 years. The pathogenic role of hereditary and environmental factors is discussed in the light of this and previous reports of twins with Crohn's disease.
D S, Rampton, R B, Stott
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Epigenetic Basis of Twin Discordance in Diseases: Future Benefits
Gynecology Obstetrics & Reproductive Medicine, 2018 Monozygotic twins share the same genotype since they are derived from the same zygote. However, monozygotic (MZ) twin siblings frequently present many phenotypic differences, such as their susceptibilities to diseases.
Ayse Banu Demir, Namik Demir
doaj +1 more source
Cells, 2022 Parkinson’s disease (PD) is one of the most common neurodegenerative diseases. Investigating individuals with the most identical genetic background is optimal for minimizing the genetic contribution to gene expression.
Ekaterina I. Semenova +7 more
doaj +1 more source
Ageing And Cancer As Diseases Of Epigenesis [PDF]
, 2009 Cancer and ageing are often said to be diseases of development. During the past fifty years, the genetic components of cancer and ageing have been intensely investigated since development, itself, was seen to be an epiphenomenon of the genome.
Gilbert, Scott F.
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Associations between birth size and later height from infancy through adulthood : an individual based pooled analysis of 28 twin cohorts participating in the CODATwins project [PDF]
, 2018 Background: There is evidence that birth size is positively associated with height in later life, but it remains unclear whether this is explained by genetic factors or the intrauterine environment.
Abramson, Lior +68 more
core +6 more sources
Biomedicine & Pharmacotherapy, 1997 Besides familial Alzheimer's disease (AD), the genetic susceptibility has also been found in sporadic cases of AD, mostly related to the apolipoprotein E polymorphism. The penetrance of AD is determined by age and probably by environmental exposure. Gene-environment interaction of a disease can be examined through studies of twins.
I, Räihä +4 more
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Kawasaki Disease in Monozygotic Twins [PDF]
Pediatric Infectious Disease Journal, 2011 Multiple lines of evidence suggest that susceptibility to Kawasaki disease (KD) is influenced by host genetics. Subclinical coronary artery vasculitis may be present in monozygotic twins who are discordant for clinical signs of KD. Health care providers should consider laboratory testing and echocardiography in both monozygotic twins when only one twin
Aubri, Kottek +2 more
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Coeliac disease in monozygotic twins [PDF]
Postgraduate Medical Journal, 1982 Summary A case of concordance for coeliac disease in monozygous twins is reported. One presented with failure to enter puberty and responded to the exclusion of gluten from her diet. The other twin was asymptomatic. They represent a well documented example of monozygous twins with concordance for coeliac disease.
D J, Shale +3 more
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A study of diabetes mellitus within a large sample of Australian twins. [PDF]
, 2008 Udgivelsesdato: 2008-FebTwin studies of diabetes mellitus can help elucidate genetic and environmental factors in etiology and can provide valuable biological samples for testing functional hypotheses, for example using expression and methylation studies
David L. Duffy +9 more
core +1 more source
Development of the preterm gut microbiome in twins at risk of necrotising enterocolitis and sepsis [PDF]
, 2013 The preterm gut microbiome is a complex dynamic community influenced by genetic and environmental factors and is implicated in the pathogenesis of necrotising enterocolitis (NEC) and sepsis.
A Darfeuille-Michaud +49 more
core +3 more sources