Results 211 to 220 of about 2,696,673 (357)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Emergency neurosurgical separation of pygopagus conjoined twins in a triplet pregnancy: illustrative case. [PDF]

J Neurosurg Case Lessons
Ali EH, Abebe YN, Haile MG, Bayable A.
europepmc   +1 more source

Colonic glycoproteins in monozygotic twins with inflammatory bowel disease

, 1991
Curt Tysk, Hermann Riedesel, Eva Hellström Lindberg, Benoît Panzini, Daniel K. Podolsky, Gunnar Järnerot   +5 more
openalex   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

In Silico Research Is Rewriting the Rules of Drug Development: Is It the End of Human Trials? [PDF]

Cureus
Lakhan SE.
europepmc   +1 more source

Hypertensive Disease in Twin Pregnancies: A Review [PDF]

, 2002
Stephan Krotz, Javier Enrique Fajardo, Sanjay Ghandi, Ashlesha Patel, Louis G. Keith   +4 more
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

MCV/Q, Medical College of Virginia Quarterly, Vol. 13 No. 4 [PDF]

, 1977

core   +1 more source

Monozygotic twins discordant for juvenile dermatomyositis: clinical, serological and gene expression studies. [PDF]

Pediatr Rheumatol Online J
Pachman LM, Khojah A, Morgan G, Marin W, James J, Kadri S, Yap KL.   +6 more
europepmc   +1 more source

Genetic and Environmental Factors in Complex Diseases: The Older Finnish Twin Cohort [PDF]

, 2002
Jaakko Kaprio, Markku Koskenvuo
openalex   +1 more source