Results 231 to 240 of about 2,696,673 (357)

Using twin studies to label disease as genetic or environmental is inappropriate [PDF]

, 2002
Alex J. MacGregor
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Understanding Heritable Variation Among Hosts in Infectious Diseases Through the Lens of Twin Studies. [PDF]

Genes (Basel)
Smatti MK, Yassine HM, Mbarek H, Boomsma DI.   +3 more
europepmc   +1 more source

Genetics vs. environment in inflammatory bowel disease: Concordance rates in 130 twin pairs

, 1995
NP Thompson, Richard Driscoll, RE Pounder, AJ Wakefield   +3 more
openalex   +1 more source

The Genetics of Coronary Heart Disease: The Contribution of Twin Studies [PDF]

, 2003
Alun Evans, G. Caroline M. van Baal, Peter McCarron, Marlies deLange, Thorkild I.A. Soerensen, Eco J. C. de Geus, Kirsten Ohm Kyvik, Nancy L. Pedersen, Tim D. Spector, Toby Andrew, Christopher Patterson, John B. Whitfield, Gu Zhu, Nicholas G. Martin, Jaakko Kaprio, Dorret I. Boomsma   +15 more
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

A case of aortic root replacement for acute type A dissection in Marfan syndrome with twin pregnancy. [PDF]

Interdiscip Cardiovasc Thorac Surg
Yang Y, Jia B, Li C, Zhu J.
europepmc   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Death after transplantation. An analysis of sixty cases [PDF]

, 1967
Dahrling, BE, Hill, RB, Rifkind, D, Starzl, TE   +3 more
core   +1 more source

Prenatal diagnosis and molecular cytogenetic analyses of a rare 15q21.3 and 16p11.2 microduplication family. [PDF]

Mol Cytogenet
Zhang F, Liao G, Wen X, Zhang C.
europepmc   +1 more source