Results 251 to 260 of about 157,074 (374)

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Twin and triplet discordance in retinopathy of prematurity: a call to integrate genomic, placental, and environmental determinants. [PDF]

Int J Retina Vitreous
Sharifi Z, Heydari M, Johari M, Yousufzai S.   +3 more
europepmc   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Longitudinal concordance for clinical characteristics in a Swedish-Danish twin population with inflammatory bowel disease [PDF]

, 2007
Jonas Halfvarson, Tine Jess, Lennart Bodin, Gunnar Järnerot, Pia Munkholm, Vibeke Binder, Curt Tysk   +6 more
openalex   +1 more source

Genetic influences on the association between DNA methylation and obesity measures: insights from a twin study design. [PDF]

Cell Biosci
Hong X, Cao H, Cao W, Lv J, Yu C, Huang T, Sun D, Liao C, Pang Y, Hu R, Gao R, Yu M, Zhou J, Wu X, Liu Y, Yin S, Gao W, Li L.   +17 more
europepmc   +1 more source

Identical Disease in Identical Twins [PDF]

BMJ, 1945
openaire   +3 more sources

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Manifest disease and motor cortex reactivity in twins discordant for schizophrenia [PDF]

, 2007
Martin Schürmann, Juha Järveläinen, Sari Avikainen, Tyrone D. Cannon, Jouko Lönnqvist, Matti Huttunen, Riitta Hari   +6 more
openalex   +1 more source

Beyond the gender data gap: co-creating equitable digital patient twins. [PDF]

Front Digit Health
Weinberger N, Hery D, Mahr D, Adler SO, Stadlbauer J, Ahrens TD.   +5 more
europepmc   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source