Results 271 to 280 of about 2,696,673 (357)
Diagnosing failure to thrive: 22q11.2 deletion syndrome in identical twins. [PDF]
BMJ Case RepVadakal S, Valladares D, Jacobsen L.
europepmc +1 more source
Molecular Oncology, EarlyView.Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns +4 more
wiley +1 more source
Transforming precision medicine: The potential of the clinical artificial intelligent single-cell framework. [PDF]
Clin Transl MedBaumgartner C, Brislinger D.
europepmc +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Twinning in Italian Holstein Cows: A Retrospective Study on Risk Factors and Its Associations with Milk Production, Fertility, and Survival. [PDF]
Vet SciGuadagnini M +3 more
europepmc +1 more source
Alzheimer's disease in twins [Letter]
, 1996 Contains fulltext : 22685___.PDF (Publisher’s version ) (Open Access)
openaire +2 more sources
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Digital twins as global learning health and disease models for preventive and personalized medicine. [PDF]
Genome MedLi X +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
Shin Ihda's "manifestation model of mood disorders" based on situation theory and twin studies. [PDF]
PCN RepEchizen K, Ohmae S.
europepmc +1 more source