Results 41 to 50 of about 45,703 (295)

Comparison of Genomic and Epigenomic Expression in Monozygotic Twins Discordant for Rett Syndrome.

PLoS ONE, 2013
Monozygotic (identical) twins have been widely used in genetic studies to determine the relative contributions of heredity and the environment in human diseases.
Kunio Miyake, Chunshu Yang, Yohei Minakuchi, Kenta Ohori, Masaki Soutome, Takae Hirasawa, Yasuhiro Kazuki, Noboru Adachi, Seiko Suzuki, Masayuki Itoh, Yu-Ichi Goto, Tomoko Andoh, Hiroshi Kurosawa, Mitsuo Oshimura, Masayuki Sasaki, Atsushi Toyoda, Takeo Kubota   +16 more
doaj   +1 more source

Manifestation of Molar-Incisor Hypomineralisation in Twins: Clinical Case Reports

Brazilian Dental Science, 2013
Molar-incisor hypomineralisation is a qualitative defect of dental tissue of systemic origin affecting one or more permanent first molars and sometimes the permanent incisors as well.
Camila Maria Bullio Fragelli, Fabiano Jeremias, Lourdes Santos-Pinto   +2 more
doaj   +1 more source

Monozygotic twins discordant for homologous Robertsonian translocation trisomy 21 of 46, XX, + 21, der (21;21) (q10; q10) in a twin-to-twin transfusion syndrome, case report

BMC Pregnancy and Childbirth, 2021
Background Monozygotic twins are nearly identical in genotype and phenotype because monozygotic twins arise from one fertilized oocyte. In all cases of discordant karyotype in monozygotic twins, trisomy 21 accounts for about one in 385,000.
Dingya Cao, Jimei Sun, Nan Li, Zhihua Li, Weiqiang Liu, Min Chen   +5 more
doaj   +1 more source

Developmental Disorders in Children Recently Diagnosed With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag, Long Vu, Ritika Miryala, Jeffrey M. Albert, Molly McVoy, Siran M. Koroukian   +5 more
wiley   +1 more source

Monozygotic twins with jejuno-ileal atresia

Journal of Pediatric Surgery Case Reports, 2019
Introduction: Intestinal atresia is a congenital anomaly of the alimentary canal characterised by discontinuity of the bowel lumen that leads to intestinal obstruction in neonates.
Dennis Mazingi, Tungamirai Gwatirisa, Bothwell A. Mbuwayesango, Taurai Zimunhu, Shamiso Chowe, Kudzayi Munanzvi, Precious Mutambanengwe, Constantine Muparadzi, Mugove Moyo   +8 more
doaj   +1 more source

Using the Non-Adoption, Abandonment, Scale-Up, Spread, and Sustainability (NASSS) Framework to Identify Barriers and Facilitators for the Implementation of Digital Twins in Cardiovascular Medicine

Sensors, 2023
A digital twin is a computer-based “virtual” representation of a complex system, updated using data from the “real” twin. Digital twins are established in product manufacturing, aviation, and infrastructure and are attracting significant attention in ...
Peter D. Winter, Timothy J. A. Chico
doaj   +1 more source

Exercise Interventions in Children, Adolescents and Young Adults With Paediatric Bone Tumours—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser, Claire Laurie, Teresa Schmidt, Irene von Luettichau, Peter Bekkering, Sabine Kesting   +5 more
wiley   +1 more source

Twin Studies in Metabolic Diseases

Annals of Medicine, 1992
The traditional role of twin studies has been to assess the relative role of genetic factors as a first step in defining the genetic architecture of complex traits. This has been based on the realization that monozygotic pairs (MZ) share all their genes, while dizygotic pairs (DZ) share 50% of their genes on average.
M, Koskenvuo, J, Kaprio, K, Romanov
openaire   +2 more sources

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou, Konstantina Dipla, Danai Faitatzidou, Fotini Iatridi, Areti Georgiou, Artemios Karagiannidis, Erasmia Sampani, Chrysostomos Dimitriadis, Aggelos Koutlas, Andreas Zafeiridis, Pantelis Sarafidis   +10 more
wiley   +1 more source

Digital twins for chronic lung diseases

European Respiratory Review
Digital twins have recently emerged in healthcare. They combine advances in cyber–physical systems, modelling and computation techniques, and enable a bidirectional flow of information between the physical and virtual entities.
Apolline Gonsard, Martin Genet, David Drummond   +2 more
doaj   +1 more source