Results 41 to 50 of about 2,696,673 (357)
Kawasaki Disease in Monozygotic Twins [PDF]
Multiple lines of evidence suggest that susceptibility to Kawasaki disease (KD) is influenced by host genetics. Subclinical coronary artery vasculitis may be present in monozygotic twins who are discordant for clinical signs of KD. Health care providers should consider laboratory testing and echocardiography in both monozygotic twins when only one twin
Jane C. Burns+2 more
openaire +3 more sources
Comparative study of dermatoglyphic patterns in identical twins
Background and aims: Dermatoglyphics has been studied extensively in chromosomal disorders and also in various diseases. Identical twins cannot be distinguished based on DNA.
R Anita Gune, Satish Patki, J Anand Pote
doaj +1 more source
Background Monozygotic twins are nearly identical in genotype and phenotype because monozygotic twins arise from one fertilized oocyte. In all cases of discordant karyotype in monozygotic twins, trisomy 21 accounts for about one in 385,000.
Dingya Cao+5 more
doaj +1 more source
The unpredictably eruptive dynamics of spruce budworm populations in eastern Canada
We examine historical population data for spruce budworm from several locations through the period 1930–1997, and use density‐dependent recruitment curves to test whether the pattern of population growth over time is more consistent with Royama's (1984; Ecological Monographs 54:429–462) linear R(t) model of harmonic oscillation at Green River New ...
Barry J. Cooke, Jacques Régnière
wiley +1 more source
A digital twin is a computer-based “virtual” representation of a complex system, updated using data from the “real” twin. Digital twins are established in product manufacturing, aviation, and infrastructure and are attracting significant attention in ...
Peter D. Winter, Timothy J. A. Chico
doaj +1 more source
The dual nature of TDC – bridging dendritic and T cells in immunity
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Genome-wide search for strabismus susceptibility loci. [PDF]
The purpose of this study was to search for chromosomal susceptibility loci for comitant strabismus. Genomic DNA was isolated from 10mL blood taken from each member of 30 nuclear families in which 2 or more siblings are affected by either esotropia or ...
Fujiwara, Hirotake+6 more
core +1 more source
Background Monozygotic twins are valuable in assessing the genetic vs environmental contribution to diseases. In the era of complete genome sequences, they allow identification of mutational mechanisms and specific genes and pathways that offer ...
C. A. Castellani+5 more
doaj +1 more source
Modeling Disease Progression in Mild Cognitive Impairment and Alzheimer's Disease with Digital Twins [PDF]
Alzheimer's Disease (AD) is a neurodegenerative disease that affects subjects in a broad range of severity and is assessed in clinical trials with multiple cognitive and functional instruments. As clinical trials in AD increasingly focus on earlier stages of the disease, especially Mild Cognitive Impairment (MCI), the ability to model subject outcomes ...
arxiv
Learning Spatio-Temporal Model of Disease Progression with NeuralODEs from Longitudinal Volumetric Data [PDF]
Robust forecasting of the future anatomical changes inflicted by an ongoing disease is an extremely challenging task that is out of grasp even for experienced healthcare professionals. Such a capability, however, is of great importance since it can improve patient management by providing information on the speed of disease progression already at the ...
arxiv