Results 51 to 60 of about 173,364,079 (241)

Correlations between physical activity and quality of life in entrepreneurs from Wrocław, Poland

BMC Sports Science, Medicine and Rehabilitation, 2023
Background Limited physical activity is one of the main reasons for the rapid increase in the prevalence of diseases of affluence, which can lead to premature deaths in adults.
Daniel Puciato, Dawid Bączkowicz, Michał Rozpara   +2 more
doaj   +1 more source

Rethinking the interplay between affluence and vulnerability to aid climate change adaptive capacity

, 2020
Affluence and vulnerability are often seen as opposite sides of a coin—with affluence generally understood as reducing forms of vulnerability through increased resilience and adaptive capacity. However, in the context of climate change and an increase in
Simon, Gregory L., Eriksen, Christine, Grenfell, Maree, Bründl, Michael, Roth, Florian, Scolobig, Anna, Prior, Timothy, Adler, Carolina, Wisner, Ben, Maduz, Linda, Thomalla, Frank, Lakhina, Shefali Juneja, Neisser, Florian, Brady, Kate   +13 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Medicine designed to combat diseases of affluence affects the early development of fish. How do plastic microparticles contribute?

, 2023
The incidence of diseases of affluence, such as diabetes mellitus, cardiovascular diseases, high blood pressure, and high cholesterol has been reported to rise.
Jana Blahova, Blahova, Jana, Doubkova, Veronika, Taştan, Yiğit, Zdenka Svobodova, Jan Mares, Mares, Jan, Aneta Hollerova, Nikola Hodkovicova, Jan Kotoucek, Frantisek Tichy, Pavla Lakdawala, Renata Hesova, Kotoucek, Jan, Denisa Medkova, Petr Marsalek, Yiğit Taştan, Tichy, Frantisek, Veronika Doubkova, Martin Faldyna, Lakdawala, Pavla, Hollerova, Aneta, Svobodova, Zdenka, Hesova, Renata, Marsalek, Petr, Hodkovicova, Nikola, Faldyna, Martin, Medkova, Denisa, Medkova, Denisa, Hollerova, Aneta, Blahova, Jana, Marsalek, Petr, Mares, Jan, Hodkovicova, Nikola, Doubkova, Veronika, Hesova, Renata, Tichy, Frantisek, Faldyna, Martin, Taştan, Yiğit, Kotoucek, Jan, Svobodova, Zdenka, Lakdawala, Pavla   +28 more
core   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Association of stress with cardiovascular diseases and risk factors in a population (ESSE-RF in Kemerovo region)

Российский кардиологический журнал, 2019
Aim. To assess the prevalence of stress and its association with socio-demographic characteristics, cardiovascular risk factors and cardiovascular diseases (CVD) in the Siberian population.Material and methods.
E. B. Shapovalova, S. A. Maksimov, E. V. Indukaeva, G. V. Artamonova   +3 more
doaj   +1 more source

Persistence of Non-Communicable Diseases, Affluence and Inequality in India [PDF]

, 2019
This study builds on the extant literature by highlighting the persistence of non-communicable diseases (NCDs), their cross-associations, and how these diseases are linked to different forms of inequality-socio-economic, gaps in affluence measured by ...
Kulkarni, Vani S., Kulkarni, Veena S., Gaiha, Raghav   +2 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source