Results 51 to 60 of about 33,005 (323)
Spatial Solution to Measure Regional Efficiency — Introducing Spatial Data Envelopment Analysis
When investigating healthcare efficiency at the regional level, the problem of interactions between neighbouring locations arises. The health of the population in a given region is related to the healthcare in other areas through a medical tourism, a ...
Alicja Olejnik +2 more
doaj +1 more source
Robert Sanborn and Angelo Giardino\u27s introduction for Volume 4, Issue 1: New Morbidities 2.
Giardino, Angelo P., Sanborn, Robert
core +2 more sources
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Lend me your ear: Frank’s sign as a non-invasive method of vascular disease risk assessment
Cardiovascular diseases are the most common cause of unfitness for work and mortality in Polish people. The recommendations of all scientific associations emphasise the key role of primary prevention of diseases of affluence; however, demographic ...
Krzysztof Pabisiak, Mariusz Bodnar
doaj +1 more source
Trends in high life satisfaction among adolescents in five Nordic countries 2002–2014 [PDF]
Life satisfaction is an important indicator when assessing positive mental health aspects in populations, including among adolescents. The aim of this study was to investigate trends over time in prevalence of high life satisfaction among adolescents ...
Currie, Candace +8 more
core +4 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Chronic heart failure is one of the diseases of affluence It relatively more often affects the elderly, as well as those who suffer from cardiovascular diseases.
Bogusława Ryś +3 more
doaj +1 more source
The importance and strategy of diabetes prevention
Diabetes has become one of the largest public health problems to date. Decreased physical activity, overnutrition, and nutrition transitions caused by changes in lifestyle contribute to the increasing incidence of chronic metabolic diseases as well as ...
Bing-Yin Shi
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source

