Results 71 to 80 of about 33,005 (323)

Poverty, depression, and anxiety: Causal evidence and mechanisms

open access: yesScience, 2020
Taxing mental health Mental equilibrium is essential for an economically productive life in both industrialized and developing countries. Accumulating evidence shows that mental ill-health and poverty tend to be traveling partners, but which is the cause?
M. Ridley   +3 more
semanticscholar   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The Occurrence of Pain in the Lumbar Spine in the Professional Group of Nurses

open access: yesPielęgniarstwo Neurologiczne i Neurochirurgiczne, 2020
Introduction. Back pain syndromes affect people inhabiting every latitude of the globe. They are more or less intense diseases of affluence affecting many professional groups, including nurses. Aim.
Agnieszka Szajerska   +2 more
doaj   +1 more source

Quality and its Improvement in the Context of Agility in Polish Organic Food Processing

open access: yesManagement Systems in Production Engineering, 2023
In a world of increasingly advanced technology and market turbulence caused by geopolitical turmoil and the spread of diseases of affluence, there is a growing need to adapt products and services to current market requirements in response to consumer ...
Dziuba Szymon
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

A world without farmers? Food production, inclusive development and ecology: Historical Evidences for a New Deal [PDF]

open access: yes, 2012
This paper questions the perspective of a "world without agriculture" which underpins the economic paradigm of "structural transformation" and "modern growth".
Benoit-Cattin, Michel   +2 more
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Association of stress with cardiovascular diseases and risk factors in a population (ESSE-RF in Kemerovo region)

open access: yesРоссийский кардиологический журнал, 2019
Aim. To assess the prevalence of stress and its association with socio-demographic characteristics, cardiovascular risk factors and cardiovascular diseases (CVD) in the Siberian population.Material and methods.
E. B. Shapovalova   +3 more
doaj   +1 more source

Neighbourhoods and self rated health: a comparison of public sector employees in London and Helsinki [PDF]

open access: yes, 2004
Study objective: Mortality and morbidity vary across neighbourhoods and larger residential areas. Effects of area deprivation on health may vary across countries, because of greater spatial separation of people occupying high and low socioeconomic ...
Lahelma, E   +3 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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