Results 81 to 90 of about 5,431 (271)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Non-communicable diseases in Indian slums: re-framing the Social Determinants of Health

open access: yesGlobal Health Action, 2018
Background: The epidemic of non-communicable diseases (NCDs) in slums has pushed its residents to heightened vulnerability. The Social Determinants of Health (SDH) framework has been used to understand the social dynamics and impact of NCDs, especially ...
Lily Beth Lumagbas   +5 more
doaj   +1 more source

The prevalence and social patterning of chronic diseases among older people in a population undergoing health transition. A 10/66 Group cross-sectional population-based survey in the Dominican Republic

open access: yesBMC Public Health, 2010
Background Very little of the increased attention towards chronic diseases in countries with low and middle incomes has been directed towards older people, who contribute 72% of all deaths, and 14% of all Disability Adjusted Life Years linked to this ...
Ortiz Maria del C   +8 more
doaj   +1 more source

Socio-demographic patterning of physical activity across migrant groups in India: results from the Indian Migration Study. [PDF]

open access: yes, 2011
OBJECTIVE: To investigate the relationship between rural to urban migration and physical activity (PA) in India. METHODS: 6,447 (42% women) participants comprising 2077 rural, 2,094 migrants and 2,276 urban were recruited.
Vaz, Mario   +41 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Morbidity profiles of Kerala and all-India: An Economic perspective [PDF]

open access: yes
This study examines the economic profiles of morbidity by disease in Kerala and all-India by estimating Engel elasticities for diseases and classifying them as between those associated with affluence and deprivation. Morbidity rates, in general, are more
M. H. Suryanarayana
core   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The impact of physical activity on the risk and severity of COVID-19 infection

open access: yesJournal of Education, Health and Sport
Introduction: A rapid outbreak of SARS-CoV-2 in the past few years caused a significant increase in the number of upper respiratory tract infections throughout the world.
Aleksandra Kujawa   +6 more
doaj   +1 more source

The Profile of Carotenoids and Other Bioactive Molecules in Various Pumpkin Fruits (Cucurbita maxima Duchesne) Cultivars

open access: yesMolecules, 2019
Bioactive compounds are significant to human nutrition. They are beneficial to health as they inhibit the development of numerous diseases of affluence. Scientists continuously search for natural sources of these components.
Bartosz Kulczyński   +1 more
doaj   +1 more source

Persistence of Non-Communicable Diseases, Affluence and Inequality in India

open access: yes, 2019
This study builds on the extant literature by highlighting the persistence of non-communicable diseases (NCDs), their cross-associations, and how these diseases are linked to different forms of inequality-socio-economic, gaps in affluence measured by ...
Kulkarni, Vani S.   +2 more
core  

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