Results 81 to 90 of about 33,005 (323)

The responsibility to protect human rights and the RtoP: prospective and retrospective responsibility [PDF]

, 2015
This article argues that -- contrary to the way that it is often framed -- the first pillar of the Responsibility to Protect (RtoP) is not best understood as an instantiation of a broader international responsibility to protect human rights. Firstly, the
Karp, David Jason
core   +1 more source

Socioeconomic and sociodemographic factors related to allergic diseases in Korean adolescents based on the Seventh Korea Youth Risk Behavior Web-based Survey: a cross-sectional study

BMC Pediatrics, 2016
BackgroundVarious international reports have shown that socioeconomic and sociodemographic variables are correlated with allergic diseases; however, little is known about how these variables affect Korean adolescents. This study was conducted to identify
Kyung-Suk Lee, Y. Rha, I. Oh, Y. Choi, S. Choi   +4 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Care services for frail older people in South Korea [PDF]

, 2001
This paper examines the changed social circumstances of older people in South Korea and specifically the increased need for formal health and social services for those who are frail and have no informal carers.
Oh, K.M., Warnes, A.M.
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Socio-economic status and physical health outcomes : the need for change in theoretical formulations : thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]

, 1995
The Black Report (Department of Health and Social Security, 1980) , which was a seminal publication in the field of health inequality, proposed several possible theoretical explanations for the phenomenon of socio-economic health inequality.
Pinfold, Alistair Mark
core  

Engaging young people in the prevention of noncommunicable diseases

Bulletin of the World Health Organization, 2016
Noncommunicable diseases (NCDs) are one of the biggest public health challenges of the 21st century.1 The social and economic impact of NCDs are threatening progress towards sustainable development.
Rosa Baker, E. Taylor, Skander Essafi, Jordan D. Jarvis, Christopher Odok   +4 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Climate patterns and mosquito-borne disease outbreaks in South and Southeast Asia

Journal of Infection and Public Health, 2018
Background: Vector-borne infectious diseases, particularly mosquito-borne, pose a substantial threat to populations throughout South and Southeast Asia. Outbreaks have affected this region several times during the early years of the 21st century, notably
Joseph L. Servadio, Samantha R. Rosenthal, Lynn Carlson, Cici Bauer   +3 more
doaj   +1 more source