Results 31 to 40 of about 145,828 (265)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Vaccination Status of Horses in Poland Based on an Internet Survey of the Horse Owners
AnimalsPreventing the spread of infectious diseases in horses requires breaking the chain of infection through appropriate prophylaxis. In Poland, where the horse population reached 273,006 in 2023, vaccinations are voluntary and primarily the responsibility of
Marta Rykala +2 more
doaj +1 more source
The Differences in Histoarchitecture of Hoof Lamellae between Obese and Lean Draft Horses
Animals, 2022 Obesity is a common problem in horses. The associations between obesity and equine metabolic syndrome (EMS) and between EMS and laminitis are known. However, there is a lack of data on whether obesity itself can affect hoof lamellae.
Magdalena Senderska-Płonowska +7 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Fatal pulmonary hemorrhage in a horse during bronchoalveolar lavage – single case report
BMC Veterinary Research, 2019 Background Pulmonary hemorrhage is a rare cause of death in horses. Hemorrhage within the respiratory tract has many causes, including mycosis of the guttural pouch, invasive procedures causing serious trauma to nasal conchae, or lung biopsy.
Mathilde S. Varegg +10 more
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Selected Large-Animal Models of Ventricular Arrhythmias
BiologyVentricular arrhythmias are among the most life-threatening cardiac rhythm disturbances. Owing to their complex pathophysiology and high mortality risk, they remain a major focus of research aimed at elucidating underlying mechanisms and improving ...
Piotr Frydrychowski +4 more
doaj +1 more source
Infiltrative laryngeal disease in dogs
Journal of Small Animal Practice, 2020 Objectives To describe the clinical features and outcome of neoplastic and inflammatory infiltrative laryngeal disease in dogs. Materials and Methods Medical records at a single referral centre were retrospectively reviewed for dogs ...
A. Dixon +3 more
openaire +3 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source