Results 81 to 90 of about 359,299 (301)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Análise de doenças do trato urinário inferior em cães. [PDF]
, 2017 Estudio epidemiológico de las enfermedades del tracto urinario caudal en perrosLower urinary tract diseases (LUTD) include different conditions that affect the urinary bladder, urethra and prostate.
BARBOSA MIRELES, MARCO ANTONIO +7 more
core +4 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Stray Dogs Cause Health Risks in Thailand [PDF]
, 2013 Around 120,000 stray dogs are currently roaming the streets of Thailand compared to the 67,000,000 people that currently live there. Although the stray dog population doesn\u27t outnumber the human population, it still should be a concern of the Thai ...
Brigham, Kadie
core +1 more source
, 2005 Governed by parasite and host factors and immunoinflammatory responses, the clinical spectrum of leishmaniasis encompasses subclinical (inapparent), localised (skin lesions), and disseminated infection (cutaneous, mucosal, or visceral).
Berman, Jonathan D +3 more
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Journal of Veterinary Research, 2019 Introduction: Pacemaker implantation is the only effective symptomatic treatment for life-threatening bradyarrhythmias. Major complications observed after implantation of cardiac pacemakers include lead dislocation, loss of pulse generator function, and ...
Noszczyk-Nowak Agnieszka +7 more
doaj +1 more source
The Institute Report from the Veterinary Virus Research Institute [PDF]
, 1960 Topics in this Institute Report include: Historical Notes; Virus Research Institute Staff: General Institute Staff, Microbiology Laboratory Staff, Cornell Research Laboratory for Diseases of Dogs Staff, Cooperating Staff; Message from the Director [James
Baker, James A. +1 more
core +3 more sources
Management of hypoadrenocorticism (Addison’s disease) in dogs
Veterinary Medicine: Research and Reports, 2018 Hypoadrenocorticism (HOAC; Addison's disease) is an endocrine condition seen in small animal practice. Dogs with this disease can present in a variety of ways from acute hypovolemic collapse to vague, chronic, waxing, and waning clinical signs. In the most common form of this disease, animals have both mineralocorticoid and glucocorticoid deficiency ...
Lathan, Patty, Thompson, Ann L.
openaire +4 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source