Results 101 to 110 of about 179,113,833 (255)

Poly(I:C)‐Activated Nasal Fibroblasts Promote Eosinophil Recruitment in CRSwNP

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by persistent mucosal inflammation and eosinophilic infiltration. Although epithelial and immune cells have been widely studied, the role of nasal fibroblasts in innate immune activation and eosinophil recruitment remains unclear.
Chaewon Shin, An‐Gi Kim, Byeong Min Yu, Woo‐Keun Kwon, Min‐Ho Hwang, Joo‐Hoo Park   +5 more
wiley   +1 more source

The views of health care professionals about selective decontamination of the digestive tract : An international, theoretically informed interview study [PDF]

, 2014
Copyright © 2014 Elsevier Inc.
Todd, L., Wells, E. C., Bolsover, D., Prior, M. E., Duncan, Eilidh M., E. Prior, Maria, Webster, F., E. Todd, Laura, Rose, L., H. Cuthbertson, Brian, C. Wells, Elisabeth, Prior, Maria E, Francis, Jill J, Bellingan, Geoff, Marshall, Andrea P, Duncan, Eilidh M, J. Francis, Jill, Todd, Laura E, Campbell, Marion K, Seppelt, I., Prior, Maria E., Rose, Louise, SuDDICU International Study Group, SuDDICU International Study Group, For the, M. Seppelt, Ian, Cuthbertson, Brian H., Newlands, Rumana S, Francis, J., Marshall, Andrea, S. Newlands, Rumana, K. Campbell, Marion, Cuthbertson, B. H., Marshall, A. P., Newlands, R. S., Campbell, M. K., Wells, Elisabeth C, Seppelt, Ian M, Bellingan, G., M. Duncan, Eilidh, Duncan, E. M., Cuthbertson, Brian H, Bolsover, Denise, Webster, Fiona   +42 more
core   +1 more source

Effects of COVID-19 Pandemic and Post-Vaccination Period on Gastroenterology Practice in Turkey

, 2023
The sudden and intense burden due to the novel coronavirus (coronavirus disease 2019) pandemic has changed the priority of many health services. The highly contagious new variants and vaccination services have greatly impacted the daily practice of ...
İbrahimhalil Düşünceli, Zeynep Gök Sargın, Ümüt Çelik   +2 more
core   +1 more source

Association of DPP4 with esophageal stricture progression and the Hippo‐YAP pathway

Animal Models and Experimental Medicine, EarlyView.
This study establishes a comprehensive translational platform for esophageal stricture (ES) research by integrating a novel rat model with clinically relevant porcine validation. This study identifies DPP4 as a gene of interest associated with ES following endoscopic submucosal dissection, demonstrating that prophylactic DPP4 inhibition attenuates ...
Rui Wu, Chen Wang, Hui‐Min Tao, Jin Huang, Wei‐Qin Li, Zhi‐Ning Fan   +5 more
wiley   +1 more source

Hospital admission for digestive diseases: Gastroenterology units offer a more effective and efficient care

, 2019
Digestive diseases imply a substantial burden for health care systems.
Milazzo, Giuseppe, Buscarini, Elisabetta, Tamburini, Cristina, Balzano, Antonio, Basili, Fulvio, Ricciardiello, Luigi, Monica, Fabio, Spolaore, Paolo, Galadini, Marco, Leandro, Gioacchino, Carle, Flavia   +10 more
core   +1 more source

Pharmacogenomic profiling of the efficacy of gemcitabine monotherapy in metastatic pancreatic cancer: Subgroup analysis of the GENESECT study

British Journal of Clinical Pharmacology, EarlyView.
Aim In the GENESECT study, no significant gemcitabine (GEM) metabolism‐related germline genetic polymorphisms (GPs) were identified because approximately 70% of patients received combination therapy with nab‐paclitaxel, which has metabolic pathways different from GEM.
Takashi Yokokawa, Daiki Tsuji, Masahiro Hatori, Kazuyoshi Kawakami, Masahiko Nakao, Takuya Yano, Yuichiro Arakawa, Keisuke Matsuo, Yasukata Ohashi, Masato Ozaka, Naoki Sasahira, Yasuhiko Sakata, Yuki Kogure, Shinya Tamaki, Atsushi Wada, Yusuke Taki, Wataru Suzuki, Kazuo Kobayashi, Hiroshi Ishii, Kunihiko Itoh, Masakazu Yamaguchi, Kenichi Suzuki   +21 more
wiley   +1 more source

CD47: an immunoregulatory nexus in liver and gastrointestinal disorders

eGastroenterology
Cluster of differentiation 47 (CD47) is a widely expressed transmembrane protein that serves as a critical immunoregulatory checkpoint in both homeostatic and pathological conditions of the digestive system.
Shuxia Wang, Josephine Otuagomah, Alana Newcomb, Taesik Gwag   +3 more
doaj   +1 more source

Progress in the Role of Mast Cells and Biomolecular Signals in the Mechanism of Postoperative Ileus: From Cellular Activation to Exploration of the Brain–Gut Axis

Gut Medicine, EarlyView.
ABSTRACT Postoperative ileus (POI) is a frequent complication after surgical procedures, predominantly manifesting as aberrant gastrointestinal motility, which markedly extends the duration of postoperative recovery for patients. The clinical duration of POI is typically modulated by intricate inflammatory cascades, with mast cells assuming a critical ...
Tian‐le Zhang, Miao‐ying Geng, Ming‐yue Shao, Gang Wang, Zhi‐wei Jiang   +4 more
wiley   +1 more source

Gut Microbiota Modulation and Functional Effects of Edible and Medicinal Fungi: Sanghuangporus vaninii as a Case Study

Gut Medicine, EarlyView.
ABSTRACT Edible and medicinal fungi exert diverse biological effects, including immunomodulatory, antitumour, and anti‐inflammatory activities, as well as the amelioration of metabolic disorders. The relationship between these effects and the gut microbiota is attracting increasing attention.
Meng Teng, Wenqi Li, Di Wang, Lanzhou Li
wiley   +1 more source

Bariatric-induced microbiome changes alter MASLD development in association with changes in the innate immune system

Frontiers in Microbiology
IntroductionMetabolic dysfunction-associated steatotic liver disease (MASLD) affects nearly 25% of the population and is the leading cause for liver-related mortality. Bariatric surgery is a well-known treatment for MASLD and obesity.
Simer Shera, William Katzka, Julianne C. Yang, Candace Chang, Nerea Arias-Jayo, Venu Lagishetty, Venu Lagishetty, Anna Balioukova, Anna Balioukova, Yijun Chen, Yijun Chen, Erik Dutson, Erik Dutson, Zhaoping Li, Zhaoping Li, Emeran A. Mayer, Emeran A. Mayer, Emeran A. Mayer, Joseph R. Pisegna, Joseph R. Pisegna, Claudia Sanmiguel, Claudia Sanmiguel, Claudia Sanmiguel, Shrey Pawar, David Zhang, Madelaine Leitman, Laura Hernandez, Jonathan P. Jacobs, Jonathan P. Jacobs, Jonathan P. Jacobs, Jonathan P. Jacobs, Tien S. Dong, Tien S. Dong, Tien S. Dong, Tien S. Dong   +34 more
doaj   +1 more source