Results 211 to 220 of about 179,113,833 (255)

External validation and optimization of the Limoges score to improve the delayed bleeding risk prediction after colorectal endoscopic submucosal dissection: the Delayed Bleeding ESD (DEBE) score. [PDF]

Endoscopy
Albéniz E, Montori S, Enguita-Germán M, Marín-Gabriel JC, Herreros de Tejada A, Wallenhorst T, Rivory J, Legros R, Degand T, Chevaux JB, Ramos-Zabala F, Le Baleur Y, Rostain F, Berger A, Rosón PJ, Terán Á, Barret M, Leclercq P, Chabrun E, Schaeffer M, Brieau B, Boukechiche S, Hijos-Mallada G, Pioche M, Jacques J, Colorectal ESD Consortium Working Group.   +25 more
europepmc   +1 more source

Evaluation of Mutation Risk Using Patient‐Derived Organoids in Patients With Lynch Syndrome

International Journal of Cancer, Volume 159, Issue 10, Page 2585-2594, 15 November 2026.
ABSTRACT Lynch syndrome (LS) is a hereditary cancer predisposition syndrome caused by germline mutation of DNA mismatch repair (MMR) genes, most notably associated with colorectal cancer. Although LS patients face high risk of CRC, risk can vary even among those with the same pathogenic MMR germline mutations. We suggest a functional assay platform for
Youmi Shin, Dong Keon Kim, Yoojeong Seo, Hyeon Hee Lee, Jihye Park, Soo Jung Park, Jae Jun Park, Jae Hee Cheon, Jongwon Oh, Sanghoo Lee, Tae Il Kim   +10 more
wiley   +1 more source

Implementation and Outcomes of a Standardized Multidisciplinary Treatment Outpatient Model in Two Pediatric Tertiary Hospitals. [PDF]

J Multidiscip Healthc
Wang M, Ye C, Gao X, Qian Y, Feng T, Shi Y.   +5 more
europepmc   +1 more source

Establishment of Salivary Gland Tumors Arising in Salivary Gland‐Specific EWSR1::ATF1 Transgenic Mice

Head &Neck, Volume 48, Issue 10, Page 2733-2744, October 2026.
ABSTRACT Background Salivary gland carcinomas are uncommon malignancies with various histological subtypes harboring fusion genes. The EWSR1::ATF1 fusion gene, resulting from a translocation between chromosomes 12 and 22, is frequently observed in hyalinizing clear cell carcinoma (HCCC). However, the role of this fusion gene in HCCC oncogenesis remains
Yuri Hirai, Yoshitaka Utsumi, Daisuke Sano, Tatsu Kuwahara, Yoshihiro Aizawa, Takashi Hatano, Hisashi Hasumi, Yutaro Soejima, Tatsukata Kawagoe, Ryosuke Jikuya, Nobuhisa Mizuki, Satoshi Fujii, Toshitaka Nagao, Nobuhiko Oridate   +13 more
wiley   +1 more source

Dynamic precision therapy in chronic gastrointestinal diseases: A focus on gastroesophageal reflux disease and inflammatory bowel disease-A narrative review and conceptual perspective. [PDF]

Ther Adv Gastroenterol
Qiu YN, Zhong BH, Zhang HH, Dai SX.
europepmc   +1 more source

Systemic Treatments for Recurrent or Metastatic Sinonasal Carcinomas: A Retrospective Multicenter Study

Head &Neck, Volume 48, Issue 10, Page 2810-2820, October 2026.
ABSTRACT Introduction Sinonasal cancers are rare and heterogeneous and pose a therapeutic challenge at an advanced stage due to the lack of data on appropriate systemic management. Methods This retrospective multicenter study analyzed 83 patients with recurrent or metastatic sinonasal carcinomas ineligible for curative treatment, treated in France ...
Marie Degrange, Mathilde Morisseau, Justin Michel, Thibaut Reverdy, Sylvain Morinière, Amaury Daste, Maxime Humbert, Caroline Viala, Pauline Corbaux, Tiffany Darbas, François‐Régis Ferrand, Valentin Favier, Camille Evrard, Diane Evrard, Delphine Farneti, Sarah Betrian‐Lagarde, Victor Sarradin   +16 more
wiley   +1 more source

Serum thiol redox-related alterations in asymptomatic first-degree relatives are associated with future Crohn's disease. [PDF]

Redox Biol
Mu K, Xue M, Huynh HQ, Griffiths AM, Turner D, Moayyedi P, Steinhart AH, Dieleman LA, Deslandres C, Bitton A, Mack DR, Jacobson K, Cino M, Aumais G, Panaccione R, Bressler B, Lee SH, Turpin W, Croitoru K, Crohn's and Colitis Canada Genetics Environment Microbial Project Research Consortium.   +19 more
europepmc   +1 more source

Musculoskeletal (Mal)adaptations in Response to a > 30 000‐km Running Challenge

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Ultra‐endurance sports are increasingly popular, yet the long‐term physiological consequences of sustained extreme training loads remain poorly understood. In particular, the effects of prolonged ultra‐endurance exercise on skeletal muscle structure, function and molecular remodelling are largely unknown.
Tomas Venckunas, Thomas Chaillou, Leonardo Cesanelli, Danguole Satkunskiene, Saulius Rutkauskas, Audrius Snieckus, Petras Minderis, Darja Nikitina, Jurgita Skieceviciene, Juozas Kupcinskas, Lorenz Webersberger, Johanna T. Lanner, Mantas Mickevicius, Birutė Gumauskiene, Asta Kuzmickaite, Andrejus Subocius, Sigitas Kamandulis   +16 more
wiley   +1 more source

Additional Role of Transabdominal Ultrasonography on Esophagogastroduodenoscopy for Uninvestigated Dyspepsia: A Prospective Study. [PDF]

Gastroenterol Res Pract
Thepwiwatjit S, Apisarnthanarak P, Pongprasobchai S.   +2 more
europepmc   +1 more source

Meta‐Analysis: Prevalence of Non‐Helicobacter pylori, Non‐NSAID Peptic Ulcer Disease

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 8, Page 1034-1045, October 2026.
A meta‐analysis of 92 studies including 60,816 patients found that non‐H. pylori, non‐NSAID represent a non‐negligible but heterogeneous component of peptic ulcer disease. Among bleeding ulcers, this proportion increased over time, potentially reflecting evolving etiologic patterns beyond H. pylori infection and NSAID exposure.
Jun Watanabe, Hiromi Sekiguchi, Takeshi Kanno, Keigo Misawa, Satoshi Sato, Yuhong Yuan, Paul Moayyedi, Tomonori Yano, Atsushi Masamune, Tomoari Kamada   +9 more
wiley   +1 more source