Results 91 to 100 of about 179,114,418 (259)

Poly(I:C)‐Activated Nasal Fibroblasts Promote Eosinophil Recruitment in CRSwNP

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by persistent mucosal inflammation and eosinophilic infiltration. Although epithelial and immune cells have been widely studied, the role of nasal fibroblasts in innate immune activation and eosinophil recruitment remains unclear.
Chaewon Shin, An‐Gi Kim, Byeong Min Yu, Woo‐Keun Kwon, Min‐Ho Hwang, Joo‐Hoo Park   +5 more
wiley   +1 more source

The views of health care professionals about selective decontamination of the digestive tract : An international, theoretically informed interview study [PDF]

, 2014
Copyright © 2014 Elsevier Inc.
Todd, L., Wells, E. C., Bolsover, D., Prior, M. E., Duncan, Eilidh M., E. Prior, Maria, Webster, F., E. Todd, Laura, Rose, L., H. Cuthbertson, Brian, C. Wells, Elisabeth, Prior, Maria E, Francis, Jill J, Bellingan, Geoff, Marshall, Andrea P, Duncan, Eilidh M, J. Francis, Jill, Todd, Laura E, Campbell, Marion K, Seppelt, I., Prior, Maria E., Rose, Louise, SuDDICU International Study Group, SuDDICU International Study Group, For the, M. Seppelt, Ian, Cuthbertson, Brian H., Newlands, Rumana S, Francis, J., Marshall, Andrea, S. Newlands, Rumana, K. Campbell, Marion, Cuthbertson, B. H., Marshall, A. P., Newlands, R. S., Campbell, M. K., Wells, Elisabeth C, Seppelt, Ian M, Bellingan, G., M. Duncan, Eilidh, Duncan, E. M., Cuthbertson, Brian H, Bolsover, Denise, Webster, Fiona   +42 more
core   +1 more source

Effects of COVID-19 Pandemic and Post-Vaccination Period on Gastroenterology Practice in Turkey

, 2023
The sudden and intense burden due to the novel coronavirus (coronavirus disease 2019) pandemic has changed the priority of many health services. The highly contagious new variants and vaccination services have greatly impacted the daily practice of ...
İbrahimhalil Düşünceli, Zeynep Gök Sargın, Ümüt Çelik   +2 more
core   +1 more source

Association of DPP4 with esophageal stricture progression and the Hippo‐YAP pathway

Animal Models and Experimental Medicine, EarlyView.
This study establishes a comprehensive translational platform for esophageal stricture (ES) research by integrating a novel rat model with clinically relevant porcine validation. This study identifies DPP4 as a gene of interest associated with ES following endoscopic submucosal dissection, demonstrating that prophylactic DPP4 inhibition attenuates ...
Rui Wu, Chen Wang, Hui‐Min Tao, Jin Huang, Wei‐Qin Li, Zhi‐Ning Fan   +5 more
wiley   +1 more source

Hospital admission for digestive diseases: Gastroenterology units offer a more effective and efficient care

, 2019
Digestive diseases imply a substantial burden for health care systems.
Milazzo, Giuseppe, Buscarini, Elisabetta, Tamburini, Cristina, Balzano, Antonio, Basili, Fulvio, Ricciardiello, Luigi, Monica, Fabio, Spolaore, Paolo, Galadini, Marco, Leandro, Gioacchino, Carle, Flavia   +10 more
core   +1 more source

Pharmacogenomic profiling of the efficacy of gemcitabine monotherapy in metastatic pancreatic cancer: Subgroup analysis of the GENESECT study

British Journal of Clinical Pharmacology, EarlyView.
Aim In the GENESECT study, no significant gemcitabine (GEM) metabolism‐related germline genetic polymorphisms (GPs) were identified because approximately 70% of patients received combination therapy with nab‐paclitaxel, which has metabolic pathways different from GEM.
Takashi Yokokawa, Daiki Tsuji, Masahiro Hatori, Kazuyoshi Kawakami, Masahiko Nakao, Takuya Yano, Yuichiro Arakawa, Keisuke Matsuo, Yasukata Ohashi, Masato Ozaka, Naoki Sasahira, Yasuhiko Sakata, Yuki Kogure, Shinya Tamaki, Atsushi Wada, Yusuke Taki, Wataru Suzuki, Kazuo Kobayashi, Hiroshi Ishii, Kunihiko Itoh, Masakazu Yamaguchi, Kenichi Suzuki   +21 more
wiley   +1 more source

CD47: an immunoregulatory nexus in liver and gastrointestinal disorders

eGastroenterology
Cluster of differentiation 47 (CD47) is a widely expressed transmembrane protein that serves as a critical immunoregulatory checkpoint in both homeostatic and pathological conditions of the digestive system.
Shuxia Wang, Josephine Otuagomah, Alana Newcomb, Taesik Gwag   +3 more
doaj   +1 more source

Establishment of Salivary Gland Tumors Arising in Salivary Gland‐Specific EWSR1::ATF1 Transgenic Mice

Head &Neck, EarlyView.
ABSTRACT Background Salivary gland carcinomas are uncommon malignancies with various histological subtypes harboring fusion genes. The EWSR1::ATF1 fusion gene, resulting from a translocation between chromosomes 12 and 22, is frequently observed in hyalinizing clear cell carcinoma (HCCC). However, the role of this fusion gene in HCCC oncogenesis remains
Yuri Hirai, Yoshitaka Utsumi, Daisuke Sano, Tatsu Kuwahara, Yoshihiro Aizawa, Takashi Hatano, Hisashi Hasumi, Yutaro Soejima, Tatsukata Kawagoe, Ryosuke Jikuya, Nobuhisa Mizuki, Satoshi Fujii, Toshitaka Nagao, Nobuhiko Oridate   +13 more
wiley   +1 more source

Innovative Therapeutic Endoscopy of the Upper Gastrointestinal Tract: Review of the Japan Gastroenterological Endoscopy Society Core Sessions. [PDF]

DEN Open
ABSTRACT The Japanese Gastroenterological Endoscopy Society (JGES) established four core sessions on endoscopic treatment for upper gastrointestinal diseases under the theme ‘Innovative Therapeutic Endoscopy’ between 2023 and 2024. This review summarizes these sessions and compiles them as a conference report. At the 105th JGES Core Session, 14 studies
Iguchi M, Michida T, Abe Y, Doyama H, Uedo N, Isomoto H, Ohta M, Fujisaki J.   +7 more
europepmc   +2 more sources

Systemic Treatments for Recurrent or Metastatic Sinonasal Carcinomas: A Retrospective Multicenter Study

Head &Neck, EarlyView.
ABSTRACT Introduction Sinonasal cancers are rare and heterogeneous and pose a therapeutic challenge at an advanced stage due to the lack of data on appropriate systemic management. Methods This retrospective multicenter study analyzed 83 patients with recurrent or metastatic sinonasal carcinomas ineligible for curative treatment, treated in France ...
Marie Degrange, Mathilde Morisseau, Justin Michel, Thibaut Reverdy, Sylvain Morinière, Amaury Daste, Maxime Humbert, Caroline Viala, Pauline Corbaux, Tiffany Darbas, François‐Régis Ferrand, Valentin Favier, Camille Evrard, Diane Evrard, Delphine Farneti, Sarah Betrian‐Lagarde, Victor Sarradin   +16 more
wiley   +1 more source