Results 101 to 110 of about 108,388 (223)

Proteomic and Metabolomic Profiling Reveal Mitochondrial Transplantation–Mediated Reprogramming in Gastric Cancer Cells

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Mitochondria provide multiple functions for cellular physiology. Transplantation of mitochondria isolated from gastric epithelial cells GES‐1 reducing the malignancy of gastric cancer cells AGS was previously reported. To elucidate the underlying mechanisms, TMT‐based proteomic analysis coupling ingenuity pathway software prediction revealed ...
Ping‐Chen Chen, Chen‐Kai Liu, Ching‐Chung Tsai, Erna Sulistyowati, Fu‐An Li, Chung‐Jung Liu, Deng‐Chyang Wu, Shih‐Hsuan Chou, Fu‐Chen Kuo, Bin Huang   +9 more
wiley   +1 more source

Knowledge Gaps, Treatment Preferences, and Unmet Clinical Needs Among Patients With Inflammatory Bowel Disease: A Cross‐Sectional Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study utilized a cross‐sectional survey via a structured questionnaire to evaluate disease‐related knowledge, treatment preferences, and unmet needs among 200 adults with confirmed inflammatory bowel disease (IBD) at a tertiary referral center.
Yi‐Chen Wu, Chien‐Ming Chen, Tony Kou, Tai‐Di Chen, Ming‐Jung Meng, Chen‐Wang Chang, Jen‐Wei Chou, Tien‐Yu Huang, Cheng‐Tang Chiu, Yu‐Bin Pan, Puo‐Hsien Le, Ming‐Yao Su   +11 more
wiley   +1 more source

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source

Breathe, Eat, Talk: Three Essential Ingredients to Quality‐of‐Life Outcomes in Movement Disorders

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Breathing, eating, and talking (BET) impairments are common yet frequently underrecognized features of movement disorders. Deficits in respiration, swallowing, voice, and speech may emerge early in the course of a disease, adversely affecting safety, participation, and quality of life.
John Dean, Lena C. O’Flynn, Michelle Ciucci, Cynthia Fox, Jessica E. Huber, Supraja Anand, Maira Rozenfeld Olchik, Jibrin S. Usman, Adam P. Vogel, Bettina Aguiar, Diana Khasanova, Dharshini Manoharan, Lorraine Ramig, Angela Roberts, Federico Rodriguez‐Porcel, Kristina Simonyan, Julie M. Barkmeier‐Kraemer   +16 more
wiley   +1 more source

Correction to: Abdominal Symptom Improvement During Clinical Trials of Tenapanor in Patients With Irritable Bowel Syndrome With Constipation: A Post Hoc Analysis. [PDF]

Am J Gastroenterol
Lembo AJ, Chey WD, Harris LA, Frazier R, Brenner DM, Chang L, Lacy BE, Edelstein S, Yang Y, Zhao S, Rosenbaum DP.   +10 more
europepmc   +1 more source

easyGBDR: An Integrated R Toolkit for Comprehensive Secondary Analysis of Global Burden of Disease Database

Med Research, EarlyView.
ABSTRACT The Global Burden of Disease (GBD) database provides essential primary data for public health research. However, its complexity and diversity pose challenges for conducting advanced secondary analyses. To address these challenges, we developed easyGBDR, an innovative integrated R toolkit designed to facilitate the secondary analysis of GBD ...
Yingying Fang, Zeyu Li, Yiming Song, Xiaolu Lin, Xiaojie Huang, Kang Wang, Quan Gan, Xu Zhang, Qingwei Zhang, Xiaobo Li   +9 more
wiley   +1 more source

Building a gastroenterology fellowship programme in Rwanda: a model of international partnerships and sustainable capacity building. [PDF]

BMJ Open Gastroenterol
Aberra H, Dua KS, Van Leeuwen DJ, Masaisa F, Salah G, Dusabejambo V, Rutaganda E, Neil K, Murayire J, Sebera E, Sendegeya A, Dadamessi I, Abebe Z, Nkeshimana M, Makrauer F, Walker T, Bensen S, Redae B.   +17 more
europepmc   +1 more source

Development and Validation of a Questionnaire‐Based Model for Households With Multiple Helicobacter pylori Infections: A Family‐Based Screening Strategy

Med Research, EarlyView.
This study developed and externally validated a questionnaire‐based household risk model to identify families with multiple Helicobacter pylori infections. Using only noninvasive, readily available household information, the model showed good discrimination and enabled a family‐based screening strategy that substantially improved detection efficiency ...
Yifan Qiu, Xianzhu Zhou, Yi Hu, Liting Shen, Jiayue Wang, Shihan Xu, Huiyun Zhu, Huabing Huang, Zhaoshen Li, Yiqi Du   +9 more
wiley   +1 more source

Large language model chatbot-based text-to-SQL application for database analyses in liver diseases and hepatology research. [PDF]

JAMIA Open
Far AT, Sun S, Jutras G, Wang MB, Burns S, Owens J, Galvez V, Somsouk M, Lai JC, Lai K, Ge J.   +10 more
europepmc   +1 more source

The Microbiome as a Mirror: Distinguishing Healthy Individuals From Chronic Constipated Patients and Identifying Those With Hidden Psychiatric Burden

Microbiota Medicine Research, EarlyView.
Gut microbiota signatures distinguish chronic constipated patients from healthy individuals, supporting noninvasive diagnostic potential. Despite challenges in identifying psychiatric‐related comorbidities, microbial alterations, particularly in neurotransmitter and inflammatory pathways, lay the groundwork for future companion diagnostics and ...
Hongyan Qi, Ting Yu, Weichen Liu, Ya Jiang, Die Chen, Li Gao, Hui Li, Yurong Tang   +7 more
wiley   +1 more source