Results 141 to 150 of about 108,388 (223)

Proteomic Analysis of Serum Extracellular Vesicles Revealed Fibulin‐3 as a Novel Predictive Biomarker for Hepatocellular Carcinoma in Patients With Chronic Hepatitis B

Hepatology Research, EarlyView.
We carried out proteomic analysis of serum extracellular vesicles to identify biomarkers predictive of hepatocellular carcinoma (HCC) development in patients with chronic hepatitis B receiving nucleos(t)ide analog therapy. Candidate proteins identified through proteomic analysis were subsequently quantified in serum by ELISA.
Emi Sometani, Kazuhiro Murai, Hayato Hikita, Jihyun Sung, Satoshi Muraoka, Hidenori Toyoda, Satoshi Tanaka, Takayuki Miyake, Shinji Kuriki, Kenji Fukumoto, Satoshi Shigeno, Yuta Myojin, Kazuki Maesaka, Kumiko Shirai, Yuki Makino, Yuki Tahata, Yoshinobu Saito, Takahiro Kodama, Ryotaro Sakamori, Jun Adachi, Tomomi Yamada, Tetsuo Takehara   +21 more
wiley   +1 more source

Liver Aging Index: A Noninvasive Score for Liver Biological Aging and Liver-Related Outcomes in Multicohorts. [PDF]

Aging Cell
Wu Z, Wu S, Song S, Huang Y, Yu C, Sun D, Pei P, Yang L, Chen Y, Du H, Walters R, Millwood I, Xu H, Yang X, Chen J, Kim SU, Petta S, Nakajima A, Tsochatzis E, Boursier J, Bugianesi E, Chan WK, Romero-Gomez M, Calleja JL, de Lédinghen V, Castéra L, Sanyal AJ, Goh GB, Newsome PN, Fan JG, Lai M, Zhou XD, Chen Z, Lv J, Li L, Wong VW, Zheng MH, Pang Y, China Kadoorie Biobank Collaborative Group and VCTE‐Prognosis Study Group.   +38 more
europepmc   +1 more source

Pemafibrate Improves Cholestatic Markers Regardless of the Presence of Primary Biliary Cholangitis

Hepatology Research, EarlyView.
Pemafibrate improves liver function markers related to bile flow in primary biliary cholangitis (PBC), but whether this effect is disease‐specific remains unclear. In this study, pemafibrate reduced these markers in patients with and without PBC, suggesting broader effects on bile flow beyond PBC.
Ryohei Tanigawa, Yoshiyuki Ueno, Hirokazu Takahashi, Ayumi Saito, Hideki Suganami, Atsushi Tanaka   +5 more
wiley   +1 more source

A case report: an unusual case of multiple jejunal foreign bodies. [PDF]

BMC Gastroenterol
Jiang Y, Chen H, Gao Z, Mei D, Xie Y.
europepmc   +1 more source

European S2k guidelines for hidradenitis suppurativa/acne inversa Part 1. Epidemiology, diagnosis and clinical assessment

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Updated S2k hidradenitis suppurativa (HS) guidelines provide expert consensus on diagnosis, assessment and comorbidities. Expanded substantially since the 2015 version, they reflect rapid growth in HS literature and aim to improve generalist‐level patient care through evidence‐informed, consensus‐based guidance.
G. B. E. Jemec, B. Villumsen, K. R. van Straalen, H. H. van der Zee, S. Valiukevičienė, T. Tzellos, J. C. Szepietowski, A. Szegedi, D. M. L. Saunte, M. Romanelli, H. Raynal, F. Prignano, E. P. Prens, M. Podda, A. Nassif, A. Molina‐Leyva, Ł. Matusiak, A. V. Marzano, B. M. McGrath, A. I. Liakou, B. Kirby, L. Kemény, E. Just, D. Ioannidis, J. R. Ingram, R. E. Hunger, B. Horváth, P. Guillem, Ø. Grimstad, E. J. Giamarellos‐Bourboulis, M. Dolenc‐Voljč, V. Del Marmol, Z. Bukvić Mokos, V. Bettoli, F. Benhadou, F. G. Bechara, C. C. Zouboulis   +36 more
wiley   +1 more source

A novel Artificial Intelligence-assisted white light endoscopic model in the diagnosis of cardia atrophy: a multicenter study. [PDF]

Ann Med Surg (Lond)
An F, Shen Y, Si S, Ji L, Zhou Z, Xu G, Lu H, Sun Q, Fu Y, Tian W, Lv J, Guo L, Chen J, Ren J, Cao H, Lu G, Zhang Y, Ke X, Zhan Q.   +18 more
europepmc   +1 more source

The Effect of Nexpowder in Reducing Post‐ESD Coagulation Syndrome in Proximal Colon Lesions: A Retrospective Multicenter Study

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Endoscopic submucosal dissection (ESD) is an established curative treatment for lateral spreading tumors and early colorectal cancer, but it can cause procedure‐related complications such as post‐ESD coagulation syndrome (PECS), which may increase healthcare utilization, prolong hospitalization, and raise medical costs.
Won Myung Lee, Jongbeom Shin, Gyeol Seong, Boram Cha, Jin Hee Maeng, Kye Sook Kwon, Bong Min Ko   +6 more
wiley   +1 more source

MASLD Management in Spain: A Nationwide Survey of Gastroenterologists Highlighting Gaps in Risk Assessment and Primary Care Coordination. [PDF]

J Clin Med
Jiménez-González C, Argos Vélez P, Cayón L, García-Garrido AB, Fontanillas Garmilla N, Cuadrado A, Iruzubieta P, Crespo J.   +7 more
europepmc   +1 more source

GLP‐1 RA Plus SGLT2i Versus Monotherapy in MASLD and Type 2 Diabetes: Three Pairwise Target Trial Emulations

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) have demonstrated cardiovascular and metabolic benefits individually; however, the comparative effectiveness of combination therapy versus monotherapy in patients with metabolic dysfunction‐associated steatotic liver ...
Mohanad A. Alkuwaiti, Faisal A. Al‐Harbi, Ahmed K. Alsaif, Ziyad M. AlSughayyir, Rayan Saleh Alsaud, Mohammed N. Aljabr, Ahmad K. Alanazi, Ahmad A. Alosaily, Abdulrhman K. Alabdulqader, Hamza Almusabeh, Rayyan F. Altemani, Ahmed Y. Azzam   +11 more
wiley   +1 more source

Comparative Study of Clinical Characteristics According to Pain Distribution in Lingual Burning Mouth Syndrome

Journal of Oral Rehabilitation, EarlyView.
Tongue pain mapping in 256 patients with lingual burning mouth syndrome identified distinct clinical phenotypes according to pain distribution. Wider pain areas were associated with higher pain intensity and poorer oral health‐related quality of life, supporting individualised assessment and targeted management.
Yoohyun Sim, Na‐Yeon Ha, Seok‐Jae Ko, Jae‐Woo Park, Jinsung Kim   +4 more
wiley   +1 more source