Results 181 to 190 of about 142,176 (246)
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley +1 more source
Burdens and patterns of gastrointestinal diseases in Thai children: an analysis based on Thai national health coverage data. [PDF]
Getsuwan S +4 more
europepmc +1 more source
In individuals with type 1 diabetes, immune cell infiltration in the colon mucosa tended to correlate with fecal and systemic markers of intestinal permeability and inflammation, as well as gastrointestinal symptoms. These findings suggest that low‐grade gut immune activation might link the intestinal barrier dysfunction with systemic endotoxin ...
Polina Zalizko +13 more
wiley +1 more source
Renaissance of Phoenix Drug Thalidomide-New Insights into Practical Clinical Application and Optimization Strategies for Managing Adverse Effects in Digestive Diseases. [PDF]
Yan X +9 more
europepmc +1 more source
ABSTRACT Background Aberrant T‐helper 1 (Th1) and Th17 cell activation is involved in the pathogenesis of inflammatory bowel disease (IBD). Psychosine is known to induce apoptosis, promote astrocyte activation, and inhibit osteoclastogenesis. However, the role of psychosine on Th1 and Th17 cell immune responses has not been previously reported. In this
Ritian Lin +4 more
wiley +1 more source
Development and psychometric test of core competency assessment scale for gastrointestinal endoscopy nurses. [PDF]
Xie G, Zeng Z, He Y, Liao X, You C.
europepmc +1 more source
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is quickly emerging as a global public health concern, primarily fueled by the rising consumption of processed and ultraprocessed foods. This global health issue, showing a 50% increase in prevalence over two decades to 38% of the global population, is now the second most common ...
Arunkumar Krishnan +9 more
wiley +1 more source
An anatomically designed duodenal stent with physiological drainage: effective endoscopic rescue in persistent perforation. [PDF]
Li SW +6 more
europepmc +1 more source
ABSTRACT Subepithelial lesions (SELs) of the upper gastrointestinal tract are commonly detected during endoscopic examinations and encompass a broad spectrum of benign, potentially malignant, and malignant tumors. While most SELs are asymptomatic and incidentally found, accurate diagnosis remains challenging due to their subepithelial location ...
Beom Jin Kim +17 more
wiley +1 more source

