Results 221 to 230 of about 106,055 (260)

Improving access to direct acting antivirals via a multimodal integrated care program in an addiction medicine clinic

open access: yesThe American Journal on Addictions, Volume 35, Issue 4, Page 534-542, July 2026.
Abstract Background and Objectives Injection drug use is a driver of hepatitis C virus (HCV) transmission, thus integrating HCV care into addiction care is likely necessary for HCV elimination. Here we describe how we integrated HCV care into our addiction medicine (AM) clinic and evaluate its effect on HCV treatment.
Arya Zandvakili   +11 more
wiley   +1 more source

Drug-Induced Liver Injury From a Novel Antifungal - Olorofim. [PDF]

open access: yesACG Case Rep J
Ranade ST   +4 more
europepmc   +1 more source

Correlation of Bile Acid Dynamics to Bulevirtide Response and Disease Severity in Patients With Hepatitis D

open access: yesAlimentary Pharmacology &Therapeutics, Volume 64, Issue 2, Page 196-207, July 2026.
Bulevirtide increases bile acid levels in most patients; however, changes in bile acids do not predict virological response or adverse events, nor do they reflect treatment adherence. After discontinuation of bulevirtide, bile acid levels rapidly decline.
Marlene Hintersteininger   +14 more
wiley   +1 more source

The Emerging Short Chain Fatty Acid Enriched Metabotype in Irritable Bowel Syndrome and Its Potential Clinical Relevance

open access: yesAlimentary Pharmacology &Therapeutics, Volume 64, Issue 2, Page 208-221, July 2026.
In a cohort of IBS‐D patients recruited to the TRITON study, faecal metabolomic profiling reveals a SCFA‐enriched metabotype associated with increased pain and urgency, altered stool characteristics and accelerated intestinal transit. ABSTRACT Background Metabolomic analysis in irritable bowel syndrome (IBS) has identified metabotypes enriched in ...
T. E. Conley   +8 more
wiley   +1 more source

Aspartate Transporter SLC1A3 Promotes Colorectal Cancer via MDM2‐p53 Pathway and M2 Macrophage Polarization

open access: yesCancer Science, Volume 117, Issue 7, Page 1813-1827, July 2026.
SLC1A3 promotes colorectal cancer progression by transporting extracellular aspartate into tumor cells, thereby activating the PKC/MDM2/p53 pathway to enhance proliferation. Reduced extracellular aspartate, combined with p53‐dependent suppression of CSF2 and IL17C, drives M2 macrophage polarization via immune modulation, macrophage recruitment, and M2 ...
Chao Deng   +9 more
wiley   +1 more source

Bridging eosinophilic esophagitis: healthcare transition from pediatric to adult patients. [PDF]

open access: yesItal J Pediatr
Savarino EV   +16 more
europepmc   +1 more source

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