Results 31 to 40 of about 147,162 (263)

Ethanol Induced Disordering of Pancreatic Acinar Cell Endoplasmic Reticulum: An ER Stress/Defective Unfolded Protein Response Model. [PDF]

, 2018
Background & aimsHeavy alcohol drinking is associated with pancreatitis, whereas moderate intake lowers the risk. Mice fed ethanol long term show no pancreas damage unless adaptive/protective responses mediating proteostasis are disrupted. Pancreatic
Abrol, Ravinder, Capri, Joseph, Cohn, Whitaker, Faull, Kym F, Freeman, Michael R, Lugea, Aurelia, Pandol, Stephen J, Piplani, Honit, Sakkiah, Sugunadevi, Su, Hsin-Yuan, Waldron, Richard T, Whitelegge, Julian P, Yang, Wei, Zhou, Bo   +13 more
core   +3 more sources

Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis

Hepatology, EarlyView., 2022
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu, Xiude Fan, Megan R. McMullen, Tatsunori Miyata, Adam Kim, Vai Pathak, Jianguo Wu, Le Z. Day, Josiah E. Hardesty, Nicole Welch, Jaividhya Dasarathy, Daniela S. Allende, Arthur J. McCullough, Jon M. Jacobs, Daniel M. Rotroff, Srinivasan Dasarathy, Laura E. Nagy   +16 more
wiley   +1 more source

Radiological diagnostic methods in gastroenterology

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim of review. To analyze the proceedings of the 22ndUnited Russian gastroenterological week devoted to radiological diagnostic methods in gastroenterology. Key points.
Z. A. Lemeshko
doaj   +1 more source

THE ETHIOPATOGENESIS AND THE ANALYSIS OF AN ANTIBIOTIC TREATMENT OF A SMALL INTESTINE BACTERIAL OVERGROWTH SYNDROME

Бюллетень сибирской медицины, 2015
Article is attempt of the critical analysis of modern approaches to treatment of a small intestine bacterial overgrowth syndrome (SIBO). SIBO now is one of the major problems in gastroenterology.
V. L. Martynov, A. Kh. Khairdinov
doaj   +1 more source

Serous cystic neoplasm of the pancreas: A multinational study of 2622 patients under the auspices of the International Association of Pancreatology and European Pancreatic Club (European Study Group on Cystic Tumors of the Pancreas) [PDF]

, 2015
OBJECTIVES: Serous cystic neoplasm (SCN) is a cystic neoplasm of the pancreas whose natural history is poorly known. The purpose of the study was to attempt to describe the natural history of SCN, including the specific mortality.
Aguero Garcete, G., Angiolini, M. R., Araujo Acuna, I., Arcidiacono, P. G., Balzano, G., Bassi, C., Bernier, B., Bissolati, M., Bolado, F., Brugge, W., Campos, V., Casadei, R., Choi, H. J., Concepcion Martin, M., Conwell, D., Crippa, S., De Angelis, C. G., Del Chiaro, M., Delhaye, M., Faccinetto, A., Falconi, M., Fern\ue1ndez Del Castillo, C., Fontana, M., Frigerio, I., Frulloni, L., Gill, R. S., Girelli, R., Gomatos, I., Ha, Y., Hirai, I., Hruban, R., Huggett, M. T., Ikeura, T., Jais, B., Jang, J. Y., Jang, K. T., Jung, W., Kang, C. M., Kang, H., Keane, M. G., Kim, M. H., Kim, S. W., Kimura, W., Kopchak, K. V., L\ue9vy, P., Lee, L. S., Lee, W. J., Lennon, A. M., Leong, R. W., Maggino, L., Malleo, G., Manfredi, R., Marchegiani, G., Matsumoto, I., Messina, O., Milanetto, Anna Caterina, Moon, J. H., Moran, R., Morana, G., Napoleon, B., Neoptolemos, J., Oh, D., Okazaki, K., Oppong, K. W., Osvaldt, A., Oua\uefssi, M., Pavey, D., Pereira, S. P., Pererva, L., Petrone, M. C., Rebours, V., Ricci, C., Rios Vives, M. A., Salvia, R., Sastre, B., Segersvard, R., Shinzeki, M., Song, D. H., Song, S. Y., Spandre, M., Sperti, Cosimo, Tang, J., Urman Fernandez, J. M., Vaquero, E. C., Wang, H., Wolfgang, C., Zaheer, A., Zerbi, A.   +87 more
core   +2 more sources

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

Hepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro, Rut Espinosa‐Sotelo, Eva Crosas‐Molist, Macarena Herranz‐Itúrbide, Daniel Caballero‐Díaz, Ania Alay, Xavier Solé, Emilio Ramos, Teresa Serrano, María L. Martínez‐Chantar, Ulla G. Knaus, José M. Cuezva, Antonio Zorzano, Esther Bertran, Isabel Fabregat   +14 more
wiley   +1 more source

The burden of clostridium difficile infection in patients with liver cirrhosis [PDF]

, 2019
Clostridium Difficile Infection (CDI) has registered a dramatically increasing incidence in the general population over the past decades. Nowadays, Clostridium Difficile is the leading cause of hospital-acquired diarrhea in Europe and North America ...
Dumitru, Andrada, Emanuela, Popoiag R, Micu, Sergiu I, Moraru, Despina, Musat, Marilena, Preda, Gabriel   +5 more
core   +2 more sources

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

Common molecular basis for MASH and hepatitis C revealed via systems biology approach

Frontiers in Oncology
BackgroundMetabolic dysfunction-associated steatohepatitis (MASH) is characterized by liver inflammation and damage caused by a buildup of fat in the liver.
Yongwei Cheng, Zihao Song, Ye Liu, Xichao Xu, Dali Zhang, Yigui Zou, Liang Liu, Yinzhen Zeng, Wenwen Li, Daming Bai, Dongling Dai   +10 more
doaj   +1 more source

Evaluation of a novel, hybrid model (Mumbai EUS II) for stepwise teaching and training in EUS-guided biliary drainage and rendezvous procedures

Endoscopy International Open, 2017
Background and aims EUS-guided biliary drainage (EUS-BD) and rendezvous (EUS-RV) are acceptable rescue options for patients with failed endoscopic retrograde cholangiopancreatography (ERCP).
Vinay Dhir, Takao Itoi, Nonthalee Pausawasdi, Mouen A. Khashab, Manuel Perez-Miranda, Siyu Sun, Do Hyun Park, Takuji Iwashita, Anthony Y. B. Teoh, Amit P. Maydeo, Khek Yu Ho   +10 more
doaj   +1 more source