Results 231 to 240 of about 268,573 (327)

Digestive Diseases in the New Health Care System

Gastroenterology, 1971
Fenton Schaffner, Carroll M. Leevy, Hans Popper, Charles S. Davidson   +3 more
openaire   +2 more sources

Mortality and hospitalization in contaminated sites with petrochemical and steel plants: a meta-regression ecological study. [PDF]

BMC Public Health
Minichilli F, Bustaffa E, Manno V, Benedetti M, Contiero P, Iavarone I, Maraschini A, Minelli G, Pasetto R, Ricci P, Zona A, Fazzo L.   +11 more
europepmc   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Mendelian Randomization Assessment of the Genetic Effects of Lipid-Lowering Drugs on Digestive System Cancers. [PDF]

Food Sci Nutr
Ma K, Wang H, Du Y, Chen T, Yang D, Li Y, Li D.   +6 more
europepmc   +1 more source

Advancements in NMN biotherapy and research updates in the field of digestive system diseases [PDF]

Guanyi Liao, Yuchen Xie, Hong Peng, Tianke Li, Xinsen Zou, Faguo Yue, Jinjun Guo, Rong Li   +7 more
openalex   +1 more source

Elevated Histone Lactylation Mediates Ferroptosis Resistance in Endometriosis Through the METTL3‐Regulated HIF1A/HMOX1 Signaling Pathway

Advanced Science, EarlyView.
This study reveals that histone lactylation, a modification derived from lactate, plays a crucial role in ferroptosis resistance in ectopic endometrial stromal cells. This resistance is mediated via the HIF1A/HMOX1 pathway regulated by METTL3. In vivo, a combination of 2‐DG and erastin shows promise as an effective treatment for endometriosis ...
Zongwen Liang, Jinming Liu, Yanling Gou, Honglin Wang, Zhi Li, Yingying Cao, Huiyan Zhang, Ruru Bai, Zongfeng Zhang   +8 more
wiley   +1 more source

Multimorbidity patterns and prevalence among geriatric patients in Japanese hospital dentistry. [PDF]

BMC Geriatr
Matsumoto K, Tsutsui T, Hashimoto R, Sakakura M, Onishi T, Akashi M.   +5 more
europepmc   +1 more source

Exploring AAV‐Mediated Gene Therapy for Inner Ear Diseases: from Preclinical Success to Clinical Potential

Advanced Science, EarlyView.
Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu, Wuhui He, Yun Xiao, Qiong Wu, Qing Zhang, Tiesong Zhang, Lei Xu, Xinyi Pang   +7 more
wiley   +1 more source

The Causal Effect of Digestive System Diseases on Risk of Erectile Dysfunction : A Mendelian Randomization Study [PDF]

Xiansheng Zhang, Peng Yang, Tianle Yang, Yukuai Ma, Zhi Cao, Pan Gao, Hui Jiang   +6 more
openalex   +1 more source

Perioperative nutritional support in patients undergoing gastrointestinal surgery: Current views with an emphasis on prehabilitation efforts. [PDF]

World J Gastrointest Surg
Triantafillidis JK.
europepmc   +1 more source