Results 231 to 240 of about 454,454 (320)

Integrin β4‐Enriched Small Extracellular Vesicle as Drug Delivery Vehicle for Targeting Pulmonary Metastasis of Hepatocellular Carcinoma

Advanced Healthcare Materials, EarlyView.
The expression of integrin β4 (ITGβ4) on small extracellular vesicle (sEV) correlates with lung‐tropism. Enrichment of ITGβ4 on sEVs enhances their lung‐targeting ability. The sEVs loaded with doxorubicin exhibit superior therapeutic efficacy in a lung metastasis mouse model.
Tung Him Ng, Aijun Liang, Maximus CF Yeung, Sze Keong Tey, Kam‐Leung Siu, Sin‐Yee Fung, Dong‐Yan Jin, Judy Wai Ping Yam   +7 more
wiley   +1 more source

Evaluation of malnutrition risk screening in hospitalized children with digestive system diseases-a single-center cross-sectional study. [PDF]

Front Pediatr
Li X, Zou Y, Zuo J, Xu T, Zeng H, Ou R, Dai D.   +6 more
europepmc   +1 more source

The role of herbal treatment and sorbents in the rehabilitation of patients with malignant disease of digestive system (review)

, 2019
M. B. Uzdenov, Б. Б. Сысуев, S. B. Evseeva, Zhanna V. Gironas   +3 more
openalex   +1 more source

Magnetic Resonance Imaging‐Based Quantification of Endosomal Escape Using Iron Oxide Nanoparticle‐Loaded Lipid Nanoparticles

Advanced Healthcare Materials, EarlyView.
The therapeutic efficacy of lipid nanoparticle(LNP)‐based drugs depends on endosomal escape. However, few methods are available for quantifying the efficiency of endosomal escape in vivo. Herein, a novel method for quantifying the endosomal escape efficiency index using magnetic resonance imaging is introduced.
Somin Lee, Jeongbin Park, Han Na Jung, Shengjun Li, Zhijun Lin, Hyung‐Jun Im   +5 more
wiley   +1 more source

Selective Lipolysis by Photoactivation of Chaperone‐Mediated Autophagy Using Adipocyte Membrane‐Coated Nanoparticle in Hydrogel

Advanced Materials, EarlyView.
Adipocyte membrane‐coated nanoparticles loaded with rosiglitazone in hydrogel offer an alternative approach to conventional obesity treatments. This system selectively targets adipocytes, inducing lipolysis by activating chaperone‐mediated autophagy through mild photothermal stimulation.
Jaehyun Choi, Junho Byun, Dongyoon Kim, Qiaoyun Li, Dongun Jin, Yeong‐jin Choi, Ho Sang Jung, Jaiwoo Lee, Yu‐Kyoung Oh   +8 more
wiley   +1 more source

Urinary Complement proteome strongly linked to diabetic kidney disease progression. [PDF]

Nat Commun
Md Dom ZI, Moon S, Satake E, Hirohama D, Palmer ND, Lampert H, Ficociello LH, Abedini A, Fernandez K, Liang X, Pickett S, Levinsohn J, O'Neil K, Dillon ST, Mauer M, Galecki AT, Freedman BI, Susztak K, Doria A, Krolewski AS, Niewczas MA.   +20 more
europepmc   +1 more source

Estimates of all cause mortality and cause specific mortality associated with proton pump inhibitors among US veterans: Cohort study [PDF]

, 2019
Al-Aly, Ziyad, Bowe, Benjamin, Li, Tingting, Xian, Hong, Xie, Yan, Yan, Yan   +5 more
core   +1 more source

Disease of the digestive system: duodenal ulcer. I. [PDF]

BMJ, 1967
openaire   +3 more sources

Development of a Vaginal Extracellular Matrix Hydrogel for Combating Genitourinary Syndrome of Menopause

Advanced Materials, EarlyView.
In this study, a vaginal specific ECM hydrogel (vECM) is developed, optimized for intravaginal topical administration, and evaluated for mitigatation of vaginal atrophy associated with menopause. When applied in a rat model of menopause, vECM improves vaginal epithelial thickness and stem cell phenotype, and despite topical application, vECM also ...
Emma I. Zelus, Jacqueline Grime, Anthony Saviola, Maxwell McCabe, Kirk C. Hansen, Marianna Alperin, Karen L. Christman   +6 more
wiley   +1 more source

Granular Hydrogels as Brittle Yield Stress Fluids

Advanced Materials, EarlyView.
This work reports the Kamani‐Donley‐Rogers yield stress fluid model can describe granular hydrogel deformation. The model robustly captures transient rheology and self‐healing behavior for granular gels of varying composition using only six parameters. This framework provides new insight regarding the effect of material parameters on granular yielding ...
Gunnar B. Thompson, Jiye Lee, Krutarth M. Kamani, Noah Flores‐Velasco, Simon A. Rogers, Brendan A. C. Harley   +5 more
wiley   +1 more source