Results 241 to 250 of about 488,369 (350)

Norbornene Homopolymerization Limits Cell Spreading in Thiol–Ene Photoclick Hydrogels

Advanced Healthcare Materials, EarlyView.
Thiol–norbornene click reactions are often used in the development of cell‐permissive 3D hydrogels. However, ene–ene crosslinks in other thiol–ene systems are known to limit permissivity. This study demonstrates the negative effects of norbornene homopolymerization on 3D cell spreading and circumvents the issue by modulating polymer degree of ...
James L. Gentry, Steven R. Caliari
wiley   +1 more source

Comparing mortality burdens attributable to ambient temperature and seasonal variation across major causes of death in Spain. [PDF]

Environ Epidemiol
Tobías A, Íñiguez C, Royé D, Hashizume M, Madaniyazi L.   +4 more
europepmc   +1 more source

Silencing Myostatin Using In Vivo Self‐Assembled siRNA Protects Against Cancer‐ and Dexamethasone‐Induced Muscle Atrophy

Advanced Healthcare Materials, EarlyView.
This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin, Azhar Anwar, Jiehao Chen, Qinghao Sun, Likun Zhou, Jie Tang, Jingwei Guo, Linbo Yan, Yongci Chen, Feng Yin, Chen‐Yu Zhang, Zigang Li, Jizheng Ma, Liyuan Sheng, Xi Chen   +14 more
wiley   +1 more source

Intestinal injury and repair: insights from hyaline fibromatosis syndrome. [PDF]

EMBO Mol Med
Lencer WI.
europepmc   +1 more source

Bioassembly of Region‐Specific Fibrocartilage Microtissues to Engineer Zonally Defined Meniscal Grafts

Advanced Healthcare Materials, EarlyView.
Meniscal microtissues are fabricated using progenitor cells isolated from the inner (iMPCs) and outer (oMPCs) regions of the meniscus. Meniscal microtissues fuse into cohesive constructs rich in sGAG and collagen. cABC treatment modulates collagen fiber formation and organization in assembled grafts.
Gabriela S. Kronemberger, Kaoutar Chattahy, Francesca D. Spagnuolo, Aliaa S. Karam, Daniel J. Kelly   +4 more
wiley   +1 more source

Pre-placement sharp angle traction-assisted endoscopic submucosal dissection for the treatment of laterally spreading tumors of the colon. [PDF]

Endoscopy
Wang J, Chen Y, Liu M, Guo X, Zhuang M, Chen F.   +5 more
europepmc   +1 more source

Analysis of the Prevalence of Digestive System Diseases in the Republic of Karakalpakstan

, 2019
S. Nurpolatova, J. Jaibergenova, G. N. Karimov   +2 more
openalex   +1 more source

Synthetic Hydrogels Incorporating Hydrolytic/Nonhydrolytic Macromer Ratios Exhibit Improved Tunability of In Vivo Degradation and Immune Responses

Advanced Healthcare Materials, EarlyView.
A synthetic 4‐arm maleimide‐terminated poly(ethylene glycol) (PEG‐4MAL) hydrogel system that combines hydrolytic ester‐linked macromer (PEG‐4eMAL) with nondegradable amide‐linked macromer (PEG‐4aMAL) in various stoichiometric ratios to tune the degradability rate. The macromers are crosslinked with dithiothreitol via thiol‐maleimide click reaction. The
Michael D. Hunckler, Sophia Kioulaphides, Karen E. Martin, Angelica L. Torres, Graham F. Barber, Stephen W. Linderman, Rebecca S. Schneider, Andrés J. García   +7 more
wiley   +1 more source

Associations between sleep changes and multimorbidity patterns in middle-aged and older Chinese adults. [PDF]

Front Public Health
Yin S, Zhang Y, Du L, Zhou J, Chen D.
europepmc   +1 more source

The role of herbal treatment and sorbents in the rehabilitation of patients with malignant disease of digestive system (review)

, 2019
M. B. Uzdenov, Б. Б. Сысуев, S. B. Evseeva, Zhanna V. Gironas   +3 more
openalex   +1 more source