Results 251 to 260 of about 454,454 (320)

Advances and Strategies in Enhancing mRNA Cancer Vaccines

Advanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang, Shengqi Chen, Haijun Hu, Yenhui Ong, Qianqian Ni   +4 more
wiley   +1 more source

Economic burden of Chagas disease in Brazil: a nationwide cost-of-illness study. [PDF]

Lancet Reg Health Am
Andrade MV, Noronha KVMS, de Souza A, Julião NA, Motta-Santos AS, Braga PEF, Bracarense H, Silva YC, Nascimento BR, Carneiro M, Martins-Melo FR, Machado IE, Perel P, Geissbühler Y, Demacq C, Ribeiro ALP.   +15 more
europepmc   +1 more source

A Programmable Nanovaccine Platform Based on M13 Bacteriophage for Personalized Cancer Vaccine and Therapy

Advanced Materials, EarlyView.
A reprogrammed (RP) phage‐based nanovaccine platform has been developed that allows single‐step assembly with precise control over adjuvanticity, antigen density, and nanoparticle size. By enhancing TLR9 activation and neoantigen display, this platform enables a potent personalized vaccine targeting tumor‐specific neoantigens. When combined with immune
Shengnan Huang, Yanpu He, Allison Madow, Huaiyao Peng, Mirielle Griffin, Jifa Qi, Mantao Huang, Heather Amoroso, Riley Abrashoff, Nimrod Heldman, Angela M. Belcher   +10 more
wiley   +1 more source

Prevalence of multimorbidity among urban-rural older adults in Mongolia: a cross-sectional study. [PDF]

BMC Public Health
Otgonbaatar U, Zhang X, Zhang M, Zhang C.   +3 more
europepmc   +1 more source

Molecular Nanoarchitectonic Sensing Layer for Analysis of Volatile Fatty Acids in Bioreactor Headspaces Using a Nanomechanical Sensor

Advanced Materials Technologies, EarlyView.
A porous crystalline sensing layer has been developed in conjunction with a nanomechanical sensor for the sensitive detection of volatile fatty acids (VFAs) in admixture at high relative humidity. The sensitive, selective sensor based on supramolecular design improves the economic viability of anaerobic digesters toward a carbon neutral society ...
Subrata Maji, Jan Hynek, Kazushi Nakada, Akiko Hori, Kosuke Minami, Jan Labuta, Mandeep K. Chahal, Daniel T. Payne, Gary J. Richards, Lok Kumar Shrestha, Katsuhiko Ariga, Yusuke Yamauchi, Genki Yoshikawa, Jonathan P. Hill   +13 more
wiley   +1 more source

Upper gastrointestinal bleeding after Roux-en-Y gastric bypass: Mallory-Weiss syndrome with marginal ulcer. [PDF]

Gastroenterol Rep (Oxf)
Zhang Y, Bian S, Li M, Zhang M, Zhang P, Liu Y, Zhang Z.   +6 more
europepmc   +1 more source

Advanced Materials in Responsible Electronics: Innovations for Sustainability, Health, and Circularity

Advanced Materials Technologies, EarlyView.
Contemporary electronic devices produce significant waste, harming ecosystems. Innovation in design, consumption, materials, and end‐of‐life management is crucial. This review explores advanced materials for sustainable and responsible electronics, highlighting their potential to reduce environmental and health hazards while improving device ...
Rawan Omar, Jiawei Yang, Tan‐Phat Huynh, Kiran Gulia, Sooyun Caroline Tavolacci, Weiwei Wu, Yan Wang, Hossam Haick   +7 more
wiley   +1 more source

Exploring molecular and modular insights into space ionizing radiation effects through heterogeneous gene regulatory networks. [PDF]

NPJ Microgravity
Yuan M, Zhang T, Liu H, Long M, Wang Q, Jiang W.   +5 more
europepmc   +1 more source

Microneedles From Shape‐Preserving Crosslinked Poly(Vinyl Alcohol) Hydrogels: Minimising Interference in Transdermal Proteomics

Advanced Materials Technologies, EarlyView.
Hydrogel‐forming microneedle patches are developed using shape‐preserving PVA‐PVP hydrogels, with and without chitosan, for minimally invasive transdermal protein biomarker sampling. The optimised patches enable efficient interstitial fluid uptake and proteomic analysis, while minimising interference.
Achmad Himawan, Robert Graham, Fabiana Volpe‐Zanutto, Huanhuan Li, Anjali K. Pandya, Andi Nur Aisyah, Rina Agustina, Juan L. Paris, Juan Dominguez‐Robles, Lalitkumar K. Vora, Andi D. Permana, Christopher J. Scott, Ryan F. Donnelly   +12 more
wiley   +1 more source

Advancements in NMN biotherapy and research updates in the field of digestive system diseases [PDF]

Guanyi Liao, Yuchen Xie, Hong Peng, Tianke Li, Xinsen Zou, Faguo Yue, Jinjun Guo, Rong Li   +7 more
openalex   +1 more source