Results 131 to 140 of about 2,843,971 (378)

8581 Unusual Case of Multifactorial Hyperthyroidism [PDF]

open access: yesJ Endocr Soc
Disclosure: D.D. Bagar: None. E. Meyers: None. M. Correia: None. Background: Nivolumab is an immune checkpoint inhibitor that is used to treat specific types of cancer, including melanoma, by increasing the ability of the immune system to detect cancer ...
Darin Daw Bagar   +2 more
europepmc   +3 more sources

DCAN: Deep Contour-Aware Networks for Accurate Gland Segmentation [PDF]

open access: yesarXiv, 2016
The morphology of glands has been used routinely by pathologists to assess the malignancy degree of adenocarcinomas. Accurate segmentation of glands from histology images is a crucial step to obtain reliable morphological statistics for quantitative diagnosis.
arxiv  

An automated and multi-parametric algorithm for objective analysis of meibography images [PDF]

open access: yesarXiv, 2020
Meibography is a non-contact imaging technique used by ophthalmologists to assist in the evaluation and diagnosis of meibomian gland dysfunction (MGD). While artificial qualitative analysis of meibography images could lead to low repeatability and efficiency and multi-parametric analysis is demanding to offer more comprehensive information in ...
arxiv  

Real-world efficacy and safety of nivolumab in previously-treated metastatic renal cell carcinoma, and association between immune-related adverse events and survival: the Italian expanded access program [PDF]

open access: yes, 2019
Background: The Italian Renal Cell Cancer Early Access Program was an expanded access program that allowed access to nivolumab, for patients (pts) with metastatic renal cell carcinoma (mRCC) prior to regulatory approval.
Buti, S   +22 more
core   +3 more sources

Advancing the Identification of Bioactive Molecules and the Construction of a Synergistic Drug Delivery System in Combating Lung Injury

open access: yesAdvanced Science, EarlyView.
Traditional Chinese Medicine (TCM), while holistic and historically esteemed, faces challenges in “miracle cures” due to slow onset, long cycles, and difficulty controlling quality. This study obtains the active ingredients, glabridin (GLA) and puerarin (PUE), from Ge‐Gen Decoction (GGD), developing a safe and effective drug delivery system, GLA‐PUE ...
Jianhong Qi   +7 more
wiley   +1 more source

Endocrine manifestations related to inherited metabolic diseases in adults

open access: yesOrphanet Journal of Rare Diseases, 2012
Most inborn errors of metabolism (IEM) are recessive, genetically transmitted diseases and are classified into 3 main groups according to their mechanisms: cellular intoxication, energy deficiency, and defects of complex molecules. They can be associated
Vantyghem Marie-Christine   +5 more
doaj   +1 more source

Gland Segmentation in Histopathology Images Using Random Forest Guided Boundary Construction [PDF]

open access: yesarXiv, 2017
Grading of cancer is important to know the extent of its spread. Prior to grading, segmentation of glandular structures is important. Manual segmentation is a time consuming process and is subject to observer bias. Hence, an automated process is required to segment the gland structures.
arxiv  

Hashimoto's thyroiditis and autoimmune gastritis [PDF]

open access: yes, 2017
The term "thyrogastric syndrome" defines the association between autoimmune thyroid disease and chronic autoimmune gastritis (CAG), and it was first described in the early 1960s.
Brusca, Nunzia   +6 more
core   +2 more sources

PCSK9 Promotes the Malignancy of Triple‐negative Breast Cancer Cells by Reducing Cholesterol Levels at the Plasma Membrane to Activate EGFR and HER3

open access: yesAdvanced Science, EarlyView.
By decreasing cholesterol and lipid raft levels in the plasma membrane, proprotein convertase subtilisin/kexin type 9 (PCSK9) boosts human epidermal growth factor receptor 1 and 3 (EGFR and HER3) activation, driving tumor growth and metastasis in triple‐negative breast cancer (TNBC).
Tianhong Li, Renfei Wu, Kathy Qian Luo
wiley   +1 more source

Dental management of patients with endocrine disorders [PDF]

open access: yes, 2010
Introduction: The endocrine system is responsible for hormonal secretion and is closely related to the central nervous system, as it diversifies its functions through the hypothalamus and pituitary glands.
Carlos Fabuel, Laura   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy