Results 171 to 180 of about 123,122 (309)

USSR space life sciences digest, issue 27 [PDF]

This is the twenty-fifth issue of NASA's Space Life Sciences Digest. It contains abstracts of 30 journal papers or book chapters published in Russian and of 2 Soviet monographs. Selected abstracts are illustrated with figures and tables from the original.
Frey, Mary Ann, Garshnek, Victoria, Rowe, Joseph, Stone, Lydia Razran, Teeter, Ronald   +4 more
core   +2 more sources

Lactylation of HMGB1 at K177 Drives Nuclear Export of TIAR to Promote Hypoxia‐Induced Stress Granule Formation

Advanced Science, EarlyView.
This study uncovers a novel mechanism in which p300‑catalyzed lactylation of HMGB1 triggers nuclear export of the HMGB1‐TIAR complex, driving TIAR‐dependent SGs formation in the cytoplasm. Mass spectrometry and mutagenesis reveals that K177 lactylation is essential for this export and subsequent SGs formation.
Chengyu Li, Zhaojun Liu, Linjie Zhu, Gang Wu, Chen Fu, Hongmin Li, Tong He, Ming Shen, Honglin Liu   +8 more
wiley   +1 more source

Autoimmune Polyglandular Syndrome Type 3 and Overlapping Autoimmune Endocrinopathies: A Case Report. [PDF]

Cureus
Nagarajan DR, Mani Jacob D, Ottu Para NK.   +2 more
europepmc   +1 more source

Targeting Hyperglycemic Bone Pre‐Metastatic Niche for Breast Cancer Bone Metastasis Therapy

Advanced Science, EarlyView.
This study reveals that breast cancer creates a hyperglycemic pre‐metastatic niche in bone prior to colonization and amplifies glucose metabolism post‐metastasis. To target this mechanism, a biomimetic enzyme‐engineered nanoplatform that disrupts tumor glycolytic pathways, proposing a therapeutic strategy to inhibit breast cancer bone metastasis by ...
Jianxin Ye, Peng Hu, Rui Zhang, Lei Zhou, Zonghua Luo, Yanan Chen, Shengzhe Ruan, Mengyi Zhu, Huaze Ding, Yike Qian, Yan Xing, Tong Meng, Changping Wang, Dianwen Song   +13 more
wiley   +1 more source

Propolis mitigates histopathological alterations in the pituitary gland and reproductive system of female albino rats subjected to cadmium toxicity. [PDF]

Vet World
Albishtue AA, Mohsin Al-Mahmmodi A, Almamoori HA, Alahmer MA.   +3 more
europepmc   +1 more source

From pituitary cells to prostate gland in health and disease: direct and indirect endocrine connections

André Sarmento‐Cabral, Antonio C. Fuentes-Fayos, Fernando Mata Ordóñez, Antonio J. León‐González, Antonio J. Martínez‐Fuentes, Manuel D. Gahete, Raúl M. Luque   +6 more
openalex   +1 more source

Assessment and treatment of patients with hypothyroidism [PDF]

, 2009
Carson, M. N.
core  

Additive Manufactured Magnetoelectric Wireless Retainer as the Periodontal Remodeler for Post‐Orthodontic Tissue Reconstruction and Relapse‐Inhibition

Advanced Science, EarlyView.
Orthodontic relapse persists as a 120‐year challenge, as traditional retainers fail to remodel tissue, causing lifelong dependence. This study demonstrates a flexible magnetoelectric retainer (FMOR) enabling wireless periodontal remodeling. FMOR cues shift periodontal ligament cell (PDLC) paracrine signaling, promoting M2 macrophages, osteogenic ...
Haoqi Lei, Jiwei Sun, Peng Chen, Li Hu, Xin Zhou, Shiqiang Gong, Qingming Tang, Xiaoqing Han, Lili Chen, Bin Su   +9 more
wiley   +1 more source

Polycystic ovary syndrome and organochlorine pesticides: exploring potential links and mechanisms. [PDF]

Front Reprod Health
Yin S, Yang W, Lin F, Jia M, Feng Y, Chen Y, Bai X, Dong Y, Mao S, Hayat K, Jin X.   +10 more
europepmc   +1 more source

Therapeutic Repair of Sperm Quality Decline Caused by Polytetrafluoroethylene

Advanced Science, EarlyView.
Exposure to PTFE (teflon), a commonly used microplastic in non‐stick cookware, significantly reduces sperm quality in both humans and mice. Specifically, PTFE induces the disruption of sperm cytoskeleton and F‐actin assembly through targeting SKAP2 in haploid spermatid.
Shiming Gan, Shumin Zhou, Jiaming Zhou, Guanghui Zhang, Jingshou Chen, Rui Liu, Kuan Sun, Sisi Li, Wenjing Xiong, Yujiao Wen, Jianzhong Sheng, Yu Zhang, Jingchao Ren, Youjiang Li, Hefeng Huang, Chen Zhang   +15 more
wiley   +1 more source