Results 31 to 40 of about 179,085,043 (197)

Mepce Restrains Ferroptosis in Prostate Cancer Through 7SK–P‐TEFb Pause Control

Advanced Science, EarlyView.
Genome‐wide CRISPR screening identifies MEPCE as a pause‐control regulator that restrains ferroptosis in prostate cancer. MEPCE loss releases P‐TEFb/CDK9 from 7SK snRNP control, enhances RNAPII Ser2 phosphorylation, and accelerates NRF2‐HMOX1‐driven labile iron accumulation and lipid peroxidation, revealing a transcriptional kinetic gate that lowers ...
Tongtong Zhang, Xiangyang Zhan, Jiexiang Zhang, Mingyue Tan, Chuanmin Chu, Guanqun Ju, Xinyu Zhai, Jianyi Gu, Huirong Zhu, Dongliang Xu   +9 more
wiley   +1 more source

SARS-CoV-2 Effects on the Male Genitourinary System

, 2022
SARS-CoV-2 infection arose in 2019 and has changed life as we know it. With our ever-advancing knowledge, therapies, and vaccines, more functions of the SARS-CoV-2 virus are being investigated outside of its pulmonary invasion. Here, we set out to review
Whitaker, Dustin, Dullea, Alexandra, Connelly, Zachary M, Ramasamy, Ranjith   +3 more
core   +2 more sources

Issues of Prevention of Urological Diseases and Dynamics of Diseases of the Genitourinary System of the Population of Osh City

Bulletin of Science and Practice
This article examines the current problem of the urogenital system morbidity in the city of Osh in the period from 2019 to 2023. Diseases of the genitourinary system pose a significant medical and social problem, especially in Kyrgyzstan, where regional climatic and socio-economic features affect the prevalence and nature of these diseases.
N. Nurlanova, B. Muratov
openaire   +1 more source

From Surgical Innovation to Population Impact: Robot‐Assisted Radical Prostatectomy and the Evolution of Surgical Public Health in Brazil's Unified Health System

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Brazil's Unified Health System (Sistema Único de Saúde, SUS) represents one of the world's largest universal health systems and provides a unique real‐world platform for integrating prevention, diagnosis, treatment, and survivorship across the cancer continuum.
Leonardo Oliveira Reis
wiley   +1 more source

Early serum sodium changes in elderly patients with nocturia receiving desmopressin

Urology Annals, 2023
Purpose: The purpose of the study is to identify early serum sodium changes that could happen in elderly patients with nocturia receiving desmopressin. Materials and Methods: This study was conducted on 28 patients complaining of nocturia and receiving ...
Mohamed Abuelnaga, Sherif Mourad, Ashraf Satour, Diaaeldin Mostafa   +3 more
doaj   +1 more source

Two Urology Faculty Positions at The Ohio State Universiity [PDF]

The Ohio State University (OSU) College of Medicine’s Department of Urology and the OSU Comprehensive Cancer Center (OSUCCC) are seeking two applicants for research-intensive tenure-track faculty positions in Basic or Translational Oncology with an ...
OSU, Urology
core   +1 more source

MRI/US Fusion Transperineal Versus Transrectral Biopsy of Prostate Cancer: Outcomes and Complication Rates, a Tertiary Medical Center Experience in the Middle East [PDF]

, 2022
OBJECTIVE: : To report on the outcomes of transperineal versus transrectal magnetic resonance imaging/ultrasound fusion biopsy of the prostate including detection of clinically significant cancer and complications. This is the first and largest series in
Labban, Muhieddine Saadeddine, Moukaddem, Hisham, El-Hajj, Albert, Abou Heidar, Nassib F., Muhammad Bulbul, Khauli, Raja Bahjat, Bulbul, Muhammad Ahmad, Nasr, Rami, Nassib Abou Heidar, Albert El-Hajj, Abou Heidar, Nassib, Raja Khauli, Khauli, Raja, Labban, Muheiddine, Bulbul, Muhammad, Nasr, Rami Wajih, Adnan El-Achkar, Mouhamad Al-Moussawy, Al-Moussawy, Mouhamad, El-Achkar, Adnan, El Hajj, Albert Elias, Muheiddine Labban, Rami Nasr, Hisham Moukaddem   +23 more
core   +1 more source

p16 Overexpression and Human Papillomavirus Positivity in More Than 1000 Penile Cancers

International Journal of Cancer, EarlyView.
ABSTRACT Penile cancer is a severe disease, and a large proportion is related to high‐risk (hr) human papillomavirus (HPV). P16 is used as an immunohistochemical marker of HPV in clinical diagnostics. Population‐based data on the prevalence of p16 in penile cancer is scarce.
Marianne Gardar Stærk, Birgitte Grønkær Toft, Christina Stilling, Johanna Elversang, Sanne Kjær‐Frifeldt, Sonja Höhle Hjulskov, Sanja Stifter‐Vretenar, Marie Aarslev Schou, Mikael Aagaard, Peter Meidahl Petersen, Jakob Kristian Jakobsen, Christian Munk, Susanne Krüger Kjær   +12 more
wiley   +1 more source

Assessment and management of dyspareunia in peri‐ and postmenopausal women: A phenotype‐based gynecologic approach

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Dyspareunia in peri‐ and postmenopausal women is common, clinically consequential, and often undertreated in gynecologic practice. Although genitourinary syndrome of menopause (GSM) is a frequent contributor, intercourse‐related pain may also reflect vestibular, pelvic floor, dermatologic, inflammatory, treatment‐related, and psychosocial ...
Marek Broul, Marcel Vančo, Jaroslava Banýrová, Aneta Hujová   +3 more
wiley   +1 more source

Microbiome-Driven Carcinogenesis and Circulating Microbial Signals in Genitourinary Cancers. [PDF]

Cancer Sci
Experimental BBN models link gut microbial metabolism and diet‐microbiome interactions to urothelial carcinogenesis, while circulating extracellular vesicle‐associated bacterial DNA signals may reflect tumor immune contexture and immune checkpoint inhibitor outcomes in urothelial and renal cell carcinoma.
Kawashima A, Jingushi K, Saito T, Uemura T, Yamamoto A, Sassi N, Horitani H, Inoguchi S, Horibe Y, Ishizuya Y, Hayashi T, Yamamoto Y, Nonomura N.   +12 more
europepmc   +2 more sources