Results 51 to 60 of about 82,334 (153)

Changes in quality of life using the Pelvic Floor Distress Inventory Short Forms 20 following vaginal surgery in women with pelvic organ prolapse: a prospective cohort study

open access: yesUrogynaecologia International Journal
Pelvic organ prolapse (POP) is a condition in which the genital organs are protruding into the vagina. Therapeutic approaches to POP consist of conservative treatment and surgery.
Anis Widyasari   +2 more
doaj   +1 more source

Nocturnal awakening secondary to pain in sleep‐related painful erection: A case report and literature review

open access: yesSleep Research, EarlyView.
Abstract A 41‐year‐old male patient presented with a 13‐year history of recurrent nocturnal penile pain associated with erections during sleep. Over the course of his illness, the patient attended outpatient clinics on 298 occasions and was hospitalized three times. The primary symptom reported was erectile pain occurring during sleep.
Liping Zhang   +5 more
wiley   +1 more source

Liquid biopsy in genitourinary oncology: Current clinical applications and future prospects across prostate, bladder, and renal cancers

open access: yesUroPrecision, EarlyView.
Abstract Liquid biopsy has emerged as a transformative approach in oncology, providing minimally invasive access to tumor‐derived biomarkers with applications across diagnosis, prognosis, therapeutic guidance, and disease monitoring. This literature review synthesizes evidence from 125 studies evaluating circulating tumor DNA, circulating tumor cells ...
Kirolos Eskandar
wiley   +1 more source

Obesity Is an Independent Risk Factor for Oligozoospermia, With Co‐Existing Hyperglycemia Exacerbating Risks of Asthenozoospermia and Elevated Sperm DNA Fragmentation

open access: yesAndrology, EarlyView.
ABSTRACT Background Metabolic health plays a critical role in maintaining male fertility and may influence offspring health. Therefore, it is necessary to incorporate metabolic indicators into the clinical assessment of male fertility. However, the relationships between different metabolic abnormalities and semen quality remain incompletely understood.
Rubing Hu   +4 more
wiley   +1 more source

Longitudinal circulating tumour DNA identifies patients at high risk of upstaging and recurrence in non‐muscle‐invasive bladder cancer

open access: yesBJU International, EarlyView.
Objectives To evaluate whether longitudinal tumour‐informed circulating tumour DNA (ctDNA) testing identifies patients at increased risk of upstaging and recurrence in high‐risk non‐muscle‐invasive bladder cancer (NMIBC). Patients and Methods A cohort of 52 patients with high‐risk NMIBC underwent serial plasma ctDNA testing using a personalised tumour ...
Can Aydogdu   +17 more
wiley   +1 more source

Outcome angioembolization in patient with high-flow priapism: A systematic review

open access: yesUrology Annals
High-flow priapism (HFP) is a rare disorder that causes prolonged, painless erections. Because it has the potential to permanently damage erectile function, HFP should be promptly treated to regain potency.
Derri Hafa Nurfajri, Dahril Dahril
doaj   +1 more source

Response evaluation of neoadjuvant therapy in MIBC: clinical trial‐derived evidence to guide practice

open access: yesBJU International, EarlyView.
Objectives To review how response to neoadjuvant therapy (NAT) is assessed in clinical trials of muscle‐invasive bladder cancer (MIBC), and to determine whether trial‐derived evidence can inform response evaluation in contemporary practice. Subjects/Patients and Methods We searched PubMed, Embase and ClinicalTrials.gov through August 2025 for ...
Roberto Contieri   +9 more
wiley   +1 more source

Combining theranostic/particle therapy with immunotherapy for the treatment of GU malignancies

open access: yesBJUI Compass
Particle therapy and radiopharmaceuticals are emerging fields in the treatment of genitourinary cancers. With these novel techniques and the ever‐growing immunotherapy options, the combinations of these therapies have the potential to improve current ...
Karin A. Skalina   +9 more
doaj   +1 more source

Sono-urethrogram versus conventional urethrogram in the assessment of urethral stricture disease: A prospective comparative study

open access: yesAsian Journal of Urology
Objective: The management of urethral stricture disease depends on the location, length of stricture, and associated urethral pathology. These parameters are obtained from preoperative imaging, with conventional urethrogram (retrograde urethrogram and ...
Akash Chitrakar   +6 more
doaj   +1 more source

Ketogenic Diet and β‐Hydroxybutyrate Suppress Bladder Cancer Growth and Enhance Anti‐PD‐L1 Immunotherapy Efficacy

open access: yesCancer Science, EarlyView.
Ketogenic diet and β‐hydroxybutyrate (β‐HB) suppress bladder cancer growth through direct anti‐tumor mechanisms and enhance anti‐PD‐L1 immunotherapy efficacy. β‐HB upregulates PD‐L1 via JAK2‐STAT3 activation and remodels the tumor immune microenvironment, sensitizing tumors to immune checkpoint blockade. ABSTRACT The limited clinical efficacy of immune
Yuan Zeng   +6 more
wiley   +1 more source

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