Results 71 to 80 of about 81,077 (211)

Multiparametric MRI in prostate cancer active surveillance: results from the Miami Active Surveillance Trial (MAST) trial

BJU International, EarlyView.
Objectives To examine the role of multiparametric magnetic resonance imaging (mpMRI) in enhancing prostate cancer (PCa) detection and selecting candidates for active surveillance (AS), given that its utility in monitoring disease progression remains unclear.
Seyed Hossein Hosseini Sharifi, Adam Williams, Jonathan T. Ryan, Tarek Ajami, Omri Falik Nativ, Sunwoo Han, Isildinha M. Reis, Nachiketh Soodana‐Prakash, Archan Khandekar, Sanjaya Swain, Oleksandr N. Kryvenko, Radka Stoyanova, Alan Pollack, Patricia R. Castillo, Bruno Nahar, Chad R. Ritch, Bruce Kava, Mark L. Gonzalgo, Dipen J. Parekh, Sanoj Punnen   +19 more
wiley   +1 more source

Endothelium‐ and epithelium‐derived novel endogenous catecholamines as modulators of the autonomic nervous system

British Journal of Pharmacology, EarlyView.
Abstract Catecholamines are classically viewed as neuronal transmitters and adrenal hormones; however, accumulating evidence demonstrates that sources other than nerve fibres and adrenal medulla play a fundamental role in local organ regulation. Physiological paradoxes, such as preserved organ function after denervation or transplantation, challenge a ...
Mariana G. de Oliveira, Edson Antunes, Fabiola Zakia Monica, Gilberto De Nucci   +3 more
wiley   +1 more source

Ketogenic Diet and β‐Hydroxybutyrate Suppress Bladder Cancer Growth and Enhance Anti‐PD‐L1 Immunotherapy Efficacy

Cancer Science, EarlyView.
Ketogenic diet and β‐hydroxybutyrate (β‐HB) suppress bladder cancer growth through direct anti‐tumor mechanisms and enhance anti‐PD‐L1 immunotherapy efficacy. β‐HB upregulates PD‐L1 via JAK2‐STAT3 activation and remodels the tumor immune microenvironment, sensitizing tumors to immune checkpoint blockade. ABSTRACT The limited clinical efficacy of immune
Yuan Zeng, Gangli Gu, Lin Yang, Bohao Fan, Haochen Cui, Lei Yan, Zhao Liu   +6 more
wiley   +1 more source

The many facets of perceived bladder health in women: Absence of symptoms and presence of healthy behaviors across the life course

Continence
Purpose:: Qualitative studies exploring bladder health are rare compared to research focusing on lower urinary tract symptoms (LUTS). Our aim was to explore adolescent and adult women’s perceptions about what constitutes a healthy bladder.
Lisa Kane Low, Beverly Rosa Williams, Diane K. Newman, Jeni Hebert-Beirne, Sonya S. Brady, Deepa R. Camenga, Aimee S. James, Jean F. Wyman, D. Yvette Lacoursiere, Kathryn L. Burgio   +9 more
doaj   +1 more source

Skeletal muscle‐specific myostatin overexpression promotes muscle oxidative capacity and fatigue resistance in transgenic mice

Experimental Physiology, EarlyView.
Abstract In addition to controlling muscle mass, myostatin may support oxidative metabolism and endurance. Loss of function through gene knockout or post‐natal blockade generally lowers muscle oxidative capacity and increases fatigability. These observations imply that myostatin activation could promote a more oxidative and less fatigable muscle ...
Andy V. Khamoui, Andrea Abraham, Janos Porszasz, Istvan Kovanecz, Silvana Constantinescu, Harry B. Rossiter, Suzanne Reisz‐Porszasz   +6 more
wiley   +1 more source

Systematic review and economic analysis of the comparative effectiveness of different inhaled corticosteroids and their usage with long-acting beta2 agonists for the treatment of chronic asthma in children under the age of 12 years [PDF]

, 2008
The limited evidence available indicates that there are no consistent significant differences in effectiveness between the three ICS licensed for use in children at either low or high dose.
Price, A., Thomson-Coon, J., G Rogers, M Pitt, D Hartwell, M Somerville, K Welch, Liu, Z., G Frampton, Shepherd, Jonathan, Main, C, Frampton, GK, Green, C, Green, C.J., Welch, K, Thompson-Coon, J., Frampton, G.K., E Loveman, Rogers, G., Stein, K, A Price, C Main, Harris, P., Welch, K., Anderson, R., Z Liu, Loveman, Emma., Price, A, C Green, Stein, K., Shepherd, J., K Stein, Liu, Z, M Smith, Rogers, G, J Thompson-Coon, Pitt, M, Rogers, G; id_orcid, Somerville, M, P Harris, Main, C., Smith, M, Hartwell, D., Takeda, A, Thompson-Coon, Jo, J Shepherd, Harris, P, Thompson-Coon, J, Smith, M., Somerville, M., Loveman, E, R Anderson, Hartwell, D, Takeda, A., Stein, Ken, A Takeda, Shepherd, J, Loveman, Emma, Anderson, R, Frampton, G K, Pitt, M.   +60 more
core   +1 more source

Single-Cell RNA Sequencing Reveals Cellular Heterogeneity and Microenvironmental Remodeling in Human Ureteral Scar Stricture Tissue

Journal of Inflammation Research
Xiaobo Ding,1– 4,* Guoxiang Li,1– 3,* Yuehan Yang,1– 3,* Zhengyao Song,1– 3 Xudong Shen,1– 3 Bingbing Hou,1– 3 Meng Zhang,1– 3 Shifang Sang,4 Jian Dai,5 Jiankang Zhang,6 Zongyao Hao,1– 3 Yang Chen,1– 3 Chaozhao Liang1– 3 ...
Ding X, Li G, Yang Y, Song Z, Shen X, Hou B, Zhang M, Sang S, Dai J, Zhang J, Hao Z, Chen Y, Liang C   +12 more
doaj  

Differentiating the Clinical and Variant Spectrum of Hardikar Syndrome From Other MED12 ‐Related Developmental Disorders

American Journal of Medical Genetics Part A, Volume 200, Issue 7, Page 1619-1650, July 2026.
ABSTRACT The rare X‐linked female‐restricted Hardikar syndrome (HDKR, OMIM # 301068) is characterized by multiple congenital anomalies including orofacial clefts, gastrointestinal, genitourinary, and cardiac anomalies, but cognitive and neurobehavioral development is rarely impaired.
Tinne Warmoeskerken, Miel Theunis, Kris Van den Bogaert, Koenraad Devriendt, Jeroen Breckpot   +4 more
wiley   +1 more source

An audit of pelvi-ureteric junction obstruction at Red Cross Children's Hospital : a six year review

, 2010
Includes bibliographical references (leaves 49-57).Pelvi-ureteric junction obstruction is an important cause of congenital renal and urinary tract abnormality. It is the commonest cause of antenatally detected hydronephrosis.
Ocheke, Isaac Ejembi
core  

Temporal Patterns and Resolution of Toxicities Following Hypofractionated Salvage Radiotherapy for Biochemical Recurrence of Prostate Cancer After Prostatectomy

The Prostate, Volume 86, Issue 10, Page 1115-1123, July 2026.
ABSTRACT Background Hypofractionated salvage radiotherapy is increasingly used for biochemical recurrence of prostate cancer post‐prostatectomy, yet its toxicity profile remains underexplored. This study evaluates the incidence, timing, and resolution of treatment‐related toxicities in this setting.
Bum‐Sup Jang, Seok‐Joo Chun, Jin Ho Kim   +2 more
wiley   +1 more source